Weighted Residue-Wise Contact Order(wRWCO)


This parameter was defined by Kinjo (Kinjo and Nishikawa, 2005; Kinjo and Miyazawa, 2008) as a local version of the contact order and it was defined as follow:

The weighted version of this index implemented in ProtDCal takes the following form:

References

Kinjo, A.R., and Nishikawa, K., 2005. Predicting secondary structures, contact numbers, and residue-wise contact orders of native protein structure from amino acid sequence using critical random networks. Biophysics 1, 67-74.

Kinjo, A.R., and Miyazawa, S., 2008. On the optimal contact potential of proteins. Chemical Physics Letters 451, 132-135.