In the next table are shown all Property Based Indices implemented in ProtDCal. The table indicates the value for an specific amino acid
Names | Mw | HP | IP | ECI | ISA | Vm | Z1 | Z2 | Z3 | Pa | Pb | Pt |
ALA | 71 | 1.8 | 6.01 | 0.05 | 62.90 | 88.6 | 0.07 | -1.73 | 0.09 | 1.29 | 0.90 | 0.78 |
ARG | 156 | -4.5 | 10.76 | 1.69 | 52.98 | 173.4 | 2.88 | 2.52 | -3.44 | 0.96 | 0.99 | 0.88 |
ASN | 114 | -3.5 | 5.41 | 1.31 | 17.87 | 114.1 | 3.22 | 1.45 | 0.84 | 0.90 | 0.76 | 1.28 |
ASP | 115 | -3.5 | 2.77 | 1.25 | 18.46 | 111.1 | 3.64 | 1.13 | 2.36 | 1.04 | 0.72 | 1.41 |
CYS | 103 | 2.5 | 5.07 | 0.15 | 78.51 | 108.5 | 0.71 | -0.97 | 4.13 | 1.11 | 0.74 | 0.80 |
GLN | 128 | -3.5 | 3.22 | 1.31 | 19.53 | 143.8 | 3.08 | 0.39 | -0.07 | 1.44 | 0.75 | 1.00 |
GLU | 129 | -3.5 | 5.65 | 1.36 | 30.19 | 138.4 | 2.18 | 0.53 | -1.14 | 1.27 | 0.80 | 0.97 |
GLY | 57 | -0.4 | 5.97 | 0.02 | 19.93 | 60.1 | 2.23 | -5.36 | 0.30 | 0.56 | 0.92 | 1.64 |
HIS | 137 | -3.2 | 7.59 | 0.56 | 87.38 | 153.2 | 2.41 | 1.74 | 1.11 | 1.22 | 1.08 | 0.69 |
ILE | 113 | 4.5 | 6.02 | 0.09 | 149.77 | 166.7 | -4.44 | -1.68 | -1.03 | 0.97 | 1.45 | 0.51 |
LEU | 113 | 3.8 | 5.98 | 0.01 | 154.35 | 166.7 | -4.19 | -1.03 | -0.98 | 1.30 | 1.02 | 0.59 |
LYS | 128 | -3.9 | 9.74 | 0.53 | 102.78 | 168.6 | 2.84 | 1.41 | -3.14 | 1.23 | 0.77 | 0.96 |
MET | 131 | 1.9 | 5.74 | 0.34 | 132.22 | 162.9 | -2.49 | -0.27 | -0.41 | 1.47 | 0.97 | 0.39 |
PHE | 147 | 2.8 | 5.48 | 0.14 | 189.42 | 189.9 | -4.92 | 1.30 | 0.45 | 1.07 | 1.32 | 0.58 |
PRO | 97 | -1.6 | 6.48 | 0.16 | 122.35 | 112.7 | -1.22 | 0.88 | 2.23 | 0.52 | 0.64 | 1.91 |
SER | 87 | -0.8 | 5.68 | 0.56 | 19.75 | 89.0 | 1.96 | -1.63 | 0.57 | 0.82 | 0.95 | 1.33 |
THR | 101 | -0.7 | 5.87 | 0.65 | 59.44 | 116.1 | 0.92 | -2.09 | -1.40 | 0.82 | 1.21 | 1.03 |
TRP | 186 | -0.9 | 5.89 | 1.08 | 179.16 | 227.8 | -4.75 | 3.65 | 0.85 | 0.99 | 1.14 | 0.75 |
TYR | 163 | -1.3 | 5.66 | 0.72 | 132.16 | 193.6 | -1.39 | 2.32 | 0.01 | 0.72 | 1.25 | 1.05 |
VAL | 99 | 4.2 | 5.97 | 0.07 | 120.91 | 140.0 | -2.69 | -2.53 | -1.29 | 0.91 | 1.49 | 0.47 |
The properties implemented are:
Zamyatin, A.A. Protein Volume in Solution, Prog. Biophys. Mol. Biol. 1972, 24, 107-123.
Hellberg, S.; Sjostrom, M.; Skagerberg, B.; Wold, S. Peptide Quantitative Structure-Activity Relationship, a Multivariate Approach. J. Med. Chem. 1987, 30, 1126-1135.
Collantes, E. R.; Dunn III, W. J. Amino Acid Side Chain Descriptors for Quantitative Structure-Activity Relationship Studies of Peptide Analogues. J. Med. Chem. 1995, 38, 2705-2713.
Hoop, T. P.; Woods, K. R. Prediction of Protein Antigenic Determinants from Amino Acid Sequences. Proc Natl Acad Sci USA. 1981, 78, 3824.
Kyte, J.; Doolitle, R. F. A Simple Method for Displaying the Hydropathic Character of a Protein. J. Mol. Biol. 1982, 157, 105-132.
Hellberg, S.; Sjostrom, M.; Skagerberg, B.; Wold, S. Peptide Quantitative Structure-Activity Relationship, a Multivariate Approach. J. Med. Chem. 1987, 30, 1126-1135.
Levitt. M. Biochemistry. 1978, 17, 4277-4285.
Katrin, S.; Karelson, M.; Jarv, J. Modeling of the Amino Acid Side Chain Effects on Peptide Conformation. Bioorg. Chem. 1999, 27, 432-433.