ENTRY       M00154            Pathway   Module
NAME        Cytochrome c oxidase
DEFINITION  (K02257+K02262+K02256+K02261+K02263+K02264+K02265+K02266+K02267+K02268+K02270-K02271+K02272-K02273+K02258+K02259+K02260)
ORTHOLOGY   K02257  COX10; protoheme IX farnesyltransferase [EC:2.5.1.141]
            K02262  COX3; cytochrome c oxidase subunit 3
            K02256  COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]
            K02261  COX2; cytochrome c oxidase subunit 2
            K02263  COX4; cytochrome c oxidase subunit 4
            K02264  COX5A; cytochrome c oxidase subunit 5a
            K02265  COX5B; cytochrome c oxidase subunit 5b
            K02266  COX6A; cytochrome c oxidase subunit 6a
            K02267  COX6B; cytochrome c oxidase subunit 6b
            K02268  COX6C; cytochrome c oxidase subunit 6c
            K02270  COX7A; cytochrome c oxidase subunit 7a
            K02271  COX7B; cytochrome c oxidase subunit 7b
            K02272  COX7C; cytochrome c oxidase subunit 7c
            K02273  COX8; cytochrome c oxidase subunit 8
            K02258  COX11; cytochrome c oxidase assembly protein subunit 11
            K02259  COX15; cytochrome c oxidase assembly protein subunit 15
            K02260  COX17; cytochrome c oxidase assembly protein subunit 17
CLASS       Pathway modules; Energy metabolism; ATP synthesis
PATHWAY     map00190  Oxidative phosphorylation
            map01100  Metabolic pathways
REACTION    R00081  C00007 + 4 C00126 + 4 C00080 -> 4 C00125 + 2 C00001
COMPOUND    C00007  Oxygen
            C00126  Ferrocytochrome c
            C00080  H+
            C00125  Ferricytochrome c
            C00001  H2O
COMMENT     Complex IV in the electron transport chain.
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