ENTRY       M00857            Signature Module
NAME        Salmonella enterica pathogenicity signature, Vi antigen
DEFINITION  K22914 K22926 K22925 K22915 K22916 K22917 (K22924+K22921+K22923+K22922)
ORTHOLOGY   K22914  tviA; Vi polysaccharide biosynthesis protein TviA
            K22926  tviB; UDP-N-acetylglucosamine 6-dehydrogenase [EC:1.1.1.136]
            K22925  tviC; UDP-N-acetylglucosaminuronic acid 4-epimerase [EC:5.1.3.-]
            K22915  tviD; Vi polysaccharide biosynthesis protein TviD
            K22916  tviE; Vi polysaccharide biosynthesis protein TviE
            K22917  vexE; Vi polysaccharide export protein VexE
            K22924  vexA; Vi polysaccharide export protein VexA
            K22921  vexB; Vi polysaccharide transport system permease protein
            K22923  vexC; Vi polysaccharide transport system ATP-binding protein [EC:3.6.3.38]
            K22922  vexD; Vi polysaccharide transport system permease protein
CLASS       Signature modules; Gene set; Pathogenicity
REFERENCE   PMID:27869515
  AUTHORS   Hu X, Chen Z, Xiong K, Wang J, Rao X, Cong Y
  TITLE     Vi capsular polysaccharide: Synthesis, virulence, and application.
  JOURNAL   Crit Rev Microbiol 43:440-452 (2017)
            DOI:10.1080/1040841X.2016.1249335
REFERENCE   PMID:25749454
  AUTHORS   Keestra-Gounder AM, Tsolis RM, Baumler AJ
  TITLE     Now you see me, now you don't: the interaction of Salmonella with innate immune receptors.
  JOURNAL   Nat Rev Microbiol 13:206-16 (2015)
            DOI:10.1038/nrmicro3428
REFERENCE   PMID:30030897
  AUTHORS   Johnson R, Mylona E, Frankel G
  TITLE     Typhoidal Salmonella: Distinctive virulence factors and pathogenesis.
  JOURNAL   Cell Microbiol 20:e12939 (2018)
            DOI:10.1111/cmi.12939
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