Koenig Human Galactose Metabolism
Description
This is a metabolism model of Human galactose metabolism in SBML format.
The content of this model has been carefully created in a manual research effort.
This file has been produced by
Matthias Koenig.
Terms of use
Copyright © 2015 Matthias Koenig.
Redistribution and use of any part of this model, with or without modification, are permitted provided that the following conditions are met:
- Redistributions of this SBML file must retain the above copyright notice, this list of conditions and the following disclaimer.
- Redistributions in a different form must reproduce the above copyright notice, this list of conditions and the following disclaimer in the documentation and/or other materials provided with the distribution.
Model : galactose_30_annotated
CreatorMatthias, Koenig, Charite Berlin, konigmatt@googlemail.com
Created: 2016-02-16 12:28
Modified: 2016-02-16 12:28
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BQB_HAS_TAXON
9606 BQB_IS BTO:0000759 UBERON:2107 FMA:7197 BTO:0000575 FMA:14515 BQB_IS_VERSION_OF PW:0000042 map00052 SMP00043 GO:0019388 REACTOME:R-HSA-70370.1 PWY-6317 |
|
type | UnitDefinitions [25] | name | units | sbo | cvterm |
---|---|---|---|---|---|
UnitDefinition | Pa_s_per_m2 | ||||
UnitDefinition | Pa_s_per_m3 | ||||
UnitDefinition | Pa_s_per_m4 | ||||
UnitDefinition | Pa | ||||
UnitDefinition | m_per_s | ||||
UnitDefinition | per_m3 | ||||
UnitDefinition | per_m2 | ||||
UnitDefinition | mole_per_s | ||||
UnitDefinition | m2_per_s | ||||
UnitDefinition | mole_per_s_per_mM2 | ||||
UnitDefinition | m3_per_skg | ||||
UnitDefinition | m2 | ||||
UnitDefinition | mM_s | ||||
UnitDefinition | per_s | ||||
UnitDefinition | m3 | ||||
UnitDefinition | mM | ||||
UnitDefinition | mole_per_s_per_mM | ||||
UnitDefinition | kg_per_m3 | ||||
UnitDefinition | per_mM | ||||
UnitDefinition | m6_per_Pa2_s2 | ||||
UnitDefinition | kg | ||||
UnitDefinition | m | ||||
UnitDefinition | s | ||||
UnitDefinition | Pa_s | ||||
UnitDefinition | m3_per_s |
type | Compartments [4] | name | size | constant | spatial dimensions | unit | derived unit | sbo | cvterm |
---|---|---|---|---|---|---|---|---|---|
Compartment | h | hepatocyte | F | 3 | m3 | ||||
Compartment | c | cytosol | F | 3 | m3 | ||||
Compartment | e | external | F | 3 | m3 | ||||
Compartment | m | plasma membrane | F | 2 | m2 |
type | Species [36] | name | compartment | boundary condition | constant | initial amount | initial concentration | substance units | derived units | sbo | cvterm |
---|---|---|---|---|---|---|---|---|---|---|---|
Species | c__ppi | pyrophosphate HO7P2 (-3) |
c | F | F | 0.008 | mole | ||||
Species | e__h2oM | water M* H2O |
e | F | F | 0.0 | mole | ||||
Species | c__glc1p | D-glucose 1-phophate C6H11O9P (-2) |
c | F | F | 0.012 | mole | ||||
Species | c__acptgal | Acceptor-galactose C6H1206R |
c | T | F | 0.0 | mole | BQB_IS
SBO:0000247 |
|||
Species | c__acpt | Acceptor (glc/gal) H2R |
c | T | F | 0.0 | mole | BQB_IS
SBO:0000247 |
|||
Species | c__udpgal | UDP-D-galactose C15H22N2O17P2 (-2) |
c | F | F | 0.11 | mole | ||||
Species | c__udp | UDP C9H11N2O12P2 (-3) |
c | F | F | 0.09 | mole | ||||
Species | c__atp | ATP C10H12N5O13P3 (-4) |
c | F | F | 2.7 | mole | ||||
Species | c__utp | UTP C9H11N2O15P3 (-4) |
c | F | F | 0.27 | mole | ||||
Species | e__gal | D-galactose C6H12O6 |
e | F | F | 0.00012 | mole | ||||
Species | c__gal1pM | D-galactose 1-phosphate M* C6H11O9P (-2) |
c | F | F | 0.0 | mole | ||||
Species | c__gal | D-galactose C6H12O6 |
c | F | F | 0.00012 | mole | ||||
Species | c__acptgalM | Acceptor-galactose M* C6H1206R |
c | T | F | 0.0 | mole | BQB_IS
SBO:0000247 |
|||
Species | c__acptglc | Acceptor-glucose C6H1206R |
c | T | F | 0.0 | mole | BQB_IS
SBO:0000247 |
|||
Species | c__galtolM | D-galactitol M* C6H14O6 |
c | F | F | 0.0 | mole | ||||
Species | e__galM | D-galactose M* C6H12O6 |
e | F | F | 0.0 | mole | ||||
Species | c__o2 | O2 O2 |
c | T | F | 0.0 | mole | ||||
Species | c__glc6p | D-glucose 6-phosphate C6H11O9P (-2) |
c | F | F | 0.12 | mole | ||||
Species | c__adp | ADP C10H12N5O10P2 (-3) |
c | F | F | 1.2 | mole | ||||
Species | h__h2oM | water M* H2O |
h | F | F | 0.0 | mole | ||||
Species | c__co2 | CO2 CO2 |
c | T | F | 0.0 | mole | ||||
Species | c__nadp | NADP C21H25N7O17P3 (-3) |
c | F | F | 0.1 | mole | ||||
Species | c__hydron | H+ H (1) |
c | T | F | 0.0 | mole | ||||
Species | c__udpgalM | UDP-D-galactose M* C15H22N2O17P2 (-2) |
c | F | F | 0.0 | mole | ||||
Species | c__galM | D-galactose M* C6H12O6 |
c | F | F | 0.0 | mole | ||||
Species | c__galtol | D-galactitol C6H14O6 |
c | F | F | 0.001 | mole | ||||
Species | c__nadph | NADPH C21H26N7O17P3 (-4) |
c | F | F | 0.1 | mole | ||||
Species | c__glc6pM | D-glucose 6-phosphate M* C6H11O9P (-2) |
c | F | F | 0.0 | mole | ||||
Species | c__glc1pM | D-glucose 1-phophate M* C6H11O9P (-2) |
c | F | F | 0.0 | mole | ||||
Species | c__udpglc | UDP-D-glucose C15H22N2O17P2 (-2) |
c | F | F | 0.34 | mole | ||||
Species | c__h2o | water H2O |
c | T | F | 0.0 | mole | ||||
Species | c__gal1p | D-galactose 1-phosphate C6H11O9P (-2) |
c | F | F | 0.001 | mole | ||||
Species | c__h2 | H2 H2 |
c | T | F | 0.0 | mole | ||||
Species | c__acptglcM | Acceptor-glucose M* C6H1206R |
c | T | F | 0.0 | mole | BQB_IS
SBO:0000247 |
|||
Species | c__udpglcM | UDP-D-glucose M* C15H22N2O17P2 (-2) |
c | F | F | 0.0 | mole | ||||
Species | c__phos | phosphate HO4P (-2) |
c | F | F | 5.0 | mole |
type | Parameters [160] | name | value | unit | derived unit | constant | sbo | cvterm |
---|---|---|---|---|---|---|---|---|
Parameter | scale_f | metabolic scaling factor | 0.31 | per_m3 | T | |||
Parameter | y_cell | width hepatocyte | 9.4e-06 | m | T | |||
Parameter | x_cell | length hepatocyte | 2.5e-05 | m | T | |||
Parameter | f_cyto | cytosolic fraction of hepatocyte | 0.4 | dimensionless | None | T | ||
Parameter | Nf | 1.0 | dimensionless | None | T | |||
Parameter | deficiency | type of galactosemia | 0.0 | dimensionless | None | T | ||
Parameter | REF_P | reference protein amount | 1.0 | mM | T | |||
Parameter | f_tissue | parenchymal fraction of liver | 0.8 | dimensionless | None | T | ||
Parameter | Vol_e | volume external compartment | m3 | T | ||||
Parameter | Vol_c | volume cytosol | m3 | T | ||||
Parameter | A_m | area plasma membrane | m2 | T | ||||
Parameter | Vol_h | volume hepatocyte | m3 | T | ||||
Parameter | c__gal_tot | mM | F | |||||
Parameter | e__gal_tot | mM | F | |||||
Parameter | c__udpglc_tot | mM | F | |||||
Parameter | c__adp_bal | ADP balance | mM | F | BQB_IS
SBO:0000196 |
|||
Parameter | c__phos_bal | Phosphate balance | mM | F | BQB_IS
SBO:0000196 |
|||
Parameter | c__glc6p_tot | mM | F | |||||
Parameter | c__gal1p_tot | mM | F | |||||
Parameter | c__scale | dimensionless | None | F | ||||
Parameter | c__galtol_tot | mM | F | |||||
Parameter | c__glc1p_tot | mM | F | |||||
Parameter | c__udpgal_tot | mM | F | |||||
Parameter | c__udp_bal | UDP balance | mM | F | BQB_IS
SBO:0000196 |
|||
Parameter | c__nadp_bal | NADP balance | mM | F | BQB_IS
SBO:0000196 |
|||
Parameter | GALK_PA | 0.024 | mole | T | ||||
Parameter | GALK_keq | 50.0 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | GALK_k_gal1p | 1.5 | mM | T | ||||
Parameter | GALK_k_adp | 0.8 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GALK_ki_gal1p | 5.3 | mM | T | BQB_IS
SBO:0000261 |
|||
Parameter | GALK_kcat | 8.7 | per_s | T | ||||
Parameter | GALK_k_gal | 0.14 | mM | T | ||||
Parameter | GALK_k_atp | 0.034 | mM | T | ||||
Parameter | c__GALK_P | 1.0 | mM | T | ||||
Parameter | c__GALK_V | mole_per_s_per_mM2 | F | |||||
Parameter | c__GALK_Vb | mole_per_s | F | |||||
Parameter | c__GALK_Vmax | mole_per_s | F | |||||
Parameter | c__GALK_dm | dimensionless | None | F | ||||
Parameter | c__GALK_Vf | mole_per_s | F | |||||
Parameter | IMP_f | 0.05 | dimensionless | None | T | |||
Parameter | IMP_k_gal1p | 0.35 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__IMP_P | 1.0 | mM | T | ||||
Parameter | c__IMP_dm | dimensionless | None | F | ||||
Parameter | c__IMP_Vf | mole_per_s | F | |||||
Parameter | c__IMP_Vmax | mole_per_s | F | |||||
Parameter | ATPS_f | 100.0 | dimensionless | None | T | |||
Parameter | ATPS_keq | 0.58 | per_mM | T | BQB_IS
SBO:0000281 |
|||
Parameter | ATPS_k_adp | 0.1 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | ATPS_k_atp | 0.5 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | ATPS_k_phos | 0.1 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__ATPS_P | 1.0 | mM | T | ||||
Parameter | c__ATPS_Vmax | mole_per_s | F | |||||
Parameter | ALDR_f | 1000000.0 | dimensionless | None | T | |||
Parameter | ALDR_keq | 4.0 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | ALDR_k_gal | 40.0 | mM | T | ||||
Parameter | ALDR_k_galtol | 40.0 | mM | T | ||||
Parameter | ALDR_k_nadp | 0.1 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | ALDR_k_nadph | 0.1 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__ALDR_P | 1.0 | mM | T | ||||
Parameter | c__ALDR_Vb | mole_per_s | F | |||||
Parameter | c__ALDR_V | mole_per_s_per_mM2 | F | |||||
Parameter | c__ALDR_Vmax | mole_per_s | F | |||||
Parameter | c__ALDR_dm | dimensionless | None | F | ||||
Parameter | c__ALDR_Vf | mole_per_s | F | |||||
Parameter | NADPR_f | 1e-10 | dimensionless | None | T | |||
Parameter | NADPR_keq | 1.0 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | NADPR_k_nadp | 0.015 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | NADPR_ki_nadph | 0.01 | mM | T | BQB_IS
SBO:0000261 |
|||
Parameter | c__NADPR_P | 1.0 | mM | T | ||||
Parameter | c__NADPR_Vmax | mole_per_s | F | |||||
Parameter | GALT_f | 0.01 | dimensionless | None | T | |||
Parameter | GALT_keq | 1.0 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | GALT_k_glc1p | 0.37 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GALT_k_udpgal | 0.5 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GALT_ki_utp | 0.13 | mM | T | BQB_IS
SBO:0000261 |
|||
Parameter | GALT_ki_udp | 0.35 | mM | T | BQB_IS
SBO:0000261 |
|||
Parameter | GALT_vm | 804.0 | dimensionless | None | T | |||
Parameter | GALT_k_gal1p | 1.25 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GALT_k_udpglc | 0.43 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__GALT_P | 1.0 | mM | T | ||||
Parameter | c__GALT_Vf | mole_per_s | F | |||||
Parameter | c__GALT_V | mole_per_s_per_mM2 | F | |||||
Parameter | c__GALT_Vmax | mole_per_s | F | |||||
Parameter | c__GALT_Vb | mole_per_s | F | |||||
Parameter | c__GALT_dm | dimensionless | None | F | ||||
Parameter | GALE_f | 0.3 | dimensionless | None | T | |||
Parameter | GALE_PA | 0.0278 | s | T | ||||
Parameter | GALE_kcat | 36.0 | per_s | T | ||||
Parameter | GALE_keq | 0.33 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | GALE_k_udpglc | 0.069 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GALE_k_udpgal | 0.3 | mM | T | ||||
Parameter | c__GALE_P | 1.0 | mM | T | ||||
Parameter | c__GALE_Vb | mole_per_s | F | |||||
Parameter | c__GALE_V | mole_per_s_per_mM | F | |||||
Parameter | c__GALE_Vmax | mole_per_s | F | |||||
Parameter | c__GALE_dm | dimensionless | None | F | ||||
Parameter | c__GALE_Vf | mole_per_s | F | |||||
Parameter | UGP_f | 2000.0 | dimensionless | None | T | |||
Parameter | UGP_keq | 0.45 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | UGP_k_utp | 0.563 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | UGP_k_glc1p | 0.172 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | UGP_k_udpglc | 0.049 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | UGP_k_ppi | 0.166 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | UGP_k_gal1p | 5.0 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | UGP_k_udpgal | 0.42 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | UGP_ki_utp | 0.643 | mM | T | BQB_IS
SBO:0000261 |
|||
Parameter | UGP_ki_udpglc | 0.643 | mM | T | BQB_IS
SBO:0000261 |
|||
Parameter | c__UGP_P | 1.0 | mM | T | ||||
Parameter | c__UGP_Vf | mole_per_s | F | |||||
Parameter | c__UGP_V | mole_per_s_per_mM2 | F | |||||
Parameter | c__UGP_Vmax | mole_per_s | F | |||||
Parameter | c__UGP_dm | dimensionless | None | F | ||||
Parameter | c__UGP_Vb | mole_per_s | F | |||||
Parameter | UGALP_f | 0.01 | dimensionless | None | T | |||
Parameter | c__UGALP_Vb | mole_per_s | F | |||||
Parameter | c__UGALP_V | mole_per_s_per_mM2 | F | |||||
Parameter | c__UGALP_Vf | mole_per_s | F | |||||
Parameter | PPASE_f | 0.05 | dimensionless | None | T | |||
Parameter | PPASE_k_ppi | 0.07 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | PPASE_n | 4.0 | dimensionless | None | T | |||
Parameter | c__PPASE_P | 1.0 | mM | T | ||||
Parameter | c__PPASE_Vmax | mole_per_s | F | |||||
Parameter | NDKU_f | 2.0 | dimensionless | None | T | |||
Parameter | NDKU_keq | 1.0 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | NDKU_k_atp | 1.33 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | NDKU_k_adp | 0.042 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | NDKU_k_utp | 27.0 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | NDKU_k_udp | 0.19 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__NDKU_P | 1.0 | mM | T | ||||
Parameter | c__NDKU_Vmax | mole_per_s | F | |||||
Parameter | PGM1_f | 50.0 | dimensionless | None | T | |||
Parameter | PGM1_keq | 10.0 | dimensionless | None | T | BQB_IS
SBO:0000281 |
||
Parameter | PGM1_k_glc6p | 0.67 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | PGM1_k_glc1p | 0.045 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__PGM1_P | 1.0 | mM | T | ||||
Parameter | c__PGM1_Vb | mole_per_s | F | |||||
Parameter | c__PGM1_V | mole_per_s_per_mM | F | |||||
Parameter | c__PGM1_Vmax | mole_per_s | F | |||||
Parameter | c__PGM1_dm | dimensionless | None | F | ||||
Parameter | c__PGM1_Vf | mole_per_s | F | |||||
Parameter | GLY_f | 0.1 | dimensionless | None | T | |||
Parameter | GLY_k_glc6p | 0.12 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GLY_k_p | 0.2 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__GLY_P | 1.0 | mM | T | ||||
Parameter | c__GLY_Vmax | mole_per_s | F | |||||
Parameter | GTF_f | 0.02 | dimensionless | None | T | |||
Parameter | GTF_k_udpgal | 0.1 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | GTF_k_udpglc | 0.1 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__GTF_P | 1.0 | mM | T | ||||
Parameter | c__GTFGAL_Vf | mole_per_s | F | |||||
Parameter | c__GTF_Vmax | mole_per_s | F | |||||
Parameter | c__GTFGLC_Vf | mole_per_s | F | |||||
Parameter | H2OT_f | 8.0 | mole_per_s | T | ||||
Parameter | H2OT_k | 1.0 | mM | T | ||||
Parameter | c__H2OT_Vmax | mole_per_s | F | |||||
Parameter | GLUT2_f | 17.0 | mole_per_s | T | ||||
Parameter | GLUT2_k_gal | 27.8 | mM | T | BQB_IS
SBO:0000027 |
|||
Parameter | c__GLUT2_P | 1.0 | mM | T | ||||
Parameter | c__GLUT2_V | mole_per_s_per_mM | F | |||||
Parameter | c__GLUT2_Vmax | mole_per_s | F |
type | InitialAssignments [4] | assignment | derived units | sbo | cvterm | ||
---|---|---|---|---|---|---|---|
InitialAssignment | Vol_e | = | |||||
InitialAssignment | Vol_c | = | |||||
InitialAssignment | A_m | = | |||||
InitialAssignment | Vol_h | = |
type | Rules [64] | assignment | derived units | sbo | cvterm | |
---|---|---|---|---|---|---|
Rule | h | = | ||||
Rule | c | = | ||||
Rule | e | = | ||||
Rule | m | = | ||||
Rule | c__gal_tot | = | ||||
Rule | e__gal_tot | = | ||||
Rule | c__udpglc_tot | = | ||||
Rule | c__adp_bal | = | ||||
Rule | c__phos_bal | = | ||||
Rule | c__glc6p_tot | = | ||||
Rule | c__gal1p_tot | = | ||||
Rule | c__scale | = | None | |||
Rule | c__galtol_tot | = | ||||
Rule | c__glc1p_tot | = | ||||
Rule | c__udpgal_tot | = | ||||
Rule | c__udp_bal | = | ||||
Rule | c__nadp_bal | = | ||||
Rule | c__GALK_V | = | ||||
Rule | c__GALK_Vb | = | ||||
Rule | c__GALK_Vmax | = | ||||
Rule | c__GALK_dm | = | None | |||
Rule | c__GALK_Vf | = | ||||
Rule | c__IMP_dm | = | None | |||
Rule | c__IMP_Vf | = | ||||
Rule | c__IMP_Vmax | = | ||||
Rule | c__ATPS_Vmax | = | ||||
Rule | c__ALDR_Vb | = | ||||
Rule | c__ALDR_V | = | ||||
Rule | c__ALDR_Vmax | = | ||||
Rule | c__ALDR_dm | = | None | |||
Rule | c__ALDR_Vf | = | ||||
Rule | c__NADPR_Vmax | = | ||||
Rule | c__GALT_Vf | = | ||||
Rule | c__GALT_V | = | ||||
Rule | c__GALT_Vmax | = | ||||
Rule | c__GALT_Vb | = | ||||
Rule | c__GALT_dm | = | None | |||
Rule | c__GALE_Vb | = | ||||
Rule | c__GALE_V | = | ||||
Rule | c__GALE_Vmax | = | ||||
Rule | c__GALE_dm | = | None | |||
Rule | c__GALE_Vf | = | ||||
Rule | c__UGP_Vf | = | ||||
Rule | c__UGP_V | = | ||||
Rule | c__UGP_Vmax | = | ||||
Rule | c__UGP_dm | = | None | |||
Rule | c__UGP_Vb | = | ||||
Rule | c__UGALP_Vb | = | ||||
Rule | c__UGALP_V | = | ||||
Rule | c__UGALP_Vf | = | ||||
Rule | c__PPASE_Vmax | = | ||||
Rule | c__NDKU_Vmax | = | ||||
Rule | c__PGM1_Vb | = | ||||
Rule | c__PGM1_V | = | ||||
Rule | c__PGM1_Vmax | = | ||||
Rule | c__PGM1_dm | = | None | |||
Rule | c__PGM1_Vf | = | ||||
Rule | c__GLY_Vmax | = | ||||
Rule | c__GTFGAL_Vf | = | ||||
Rule | c__GTF_Vmax | = | ||||
Rule | c__GTFGLC_Vf | = | ||||
Rule | c__H2OT_Vmax | = | ||||
Rule | c__GLUT2_V | = | ||||
Rule | c__GLUT2_Vmax | = |
type | Reactions [31] | name | equation | modifiers | formula | derived units | sbo | cvterm | |
---|---|---|---|---|---|---|---|---|---|
Reaction | c__GALK | Galactokinase [c__] | ⇆ | c__gal + c__atp ⇆ c__gal1p + c__adp + c__hydron |
c__galM c__gal1pM |
BQB_IS
SBO:0000176 2.7.1.6 P51570 R01092 13556 REACTOME:R-HSA-70355.1 BQB_HAS_PROPERTY 230200 BQB_IS_DESCRIBED_BY 12694189 |
|||
Reaction | c__GALKM | Galactokinase M [c__] | ➞ | c__galM + c__atp ➞ c__gal1pM + c__adp + c__hydron |
c__gal c__gal1p |
BQB_IS
SBO:0000176 2.7.1.6 P51570 R01092 13556 REACTOME:R-HSA-70355.1 BQB_HAS_PROPERTY 230200 BQB_IS_DESCRIBED_BY 12694189 |
|||
Reaction | c__IMP | Inositol monophosphatase [c__] | ➞ | c__gal1p + c__h2o ➞ c__gal + c__phos |
c__gal1pM |
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Reaction | c__IMPM | Inositol monophosphatase M [c__] | ➞ | c__gal1pM + c__h2o ➞ c__galM + c__phos |
c__gal1p |
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Reaction | c__ATPS | ATP synthase [c__] | ⇆ | c__adp + c__phos + c__hydron ⇆ c__atp + c__h2o | |||||
Reaction | c__ALDR | Aldose reductase [c__] | ⇆ | c__gal + c__nadph + c__hydron ⇆ c__galtol + c__nadp |
c__galM c__galtolM |
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Reaction | c__ALDRM | Aldose reductase M [c__] | ⇆ | c__galM + c__nadph + c__hydron ⇆ c__galtolM + c__nadp |
c__gal c__galtol |
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Reaction | c__NADPR | NADP Reductase [c__] | ⇆ | c__nadp + c__h2 ⇆ c__nadph + c__hydron | |||||
Reaction | c__GALT | Galactose-1-phosphate uridyl transferase [c__] | ⇆ | c__gal1p + c__udpglc ⇆ c__glc1p + c__udpgal |
c__utp c__udp c__gal1pM c__udpglcM c__glc1p c__udpgalM |
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Reaction | c__GALTM1 | Galactose-1-phosphate uridyl transferase M1 [c__] | ⇆ | c__gal1pM + c__udpglc ⇆ c__glc1p + c__udpgalM |
c__utp c__udp c__gal1p c__udpglcM c__glc1pM c__udpgal |
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Reaction | c__GALTM2 | Galactose-1-phosphate uridyl transferase M2 [c__] | ⇆ | c__gal1p + c__udpglcM ⇆ c__glc1pM + c__udpgal |
c__utp c__udp c__gal1pM c__udpglc c__glc1p c__udpgalM |
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Reaction | c__GALTM3 | Galactose-1-phosphate uridyl transferase M3 [c__] | ⇆ | c__gal1pM + c__udpglcM ⇆ c__glc1pM + c__udpgalM |
c__utp c__udp c__gal1p c__udpglc c__glc1p c__udpgal |
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Reaction | c__GALE | UDP-glucose 4-epimerase [c__] | ⇆ | c__udpglc ⇆ c__udpgal |
c__udpglcM c__udpgalM |
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Reaction | c__GALEM | UDP-glucose 4-epimerase M [c__] | ⇆ | c__udpglcM ⇆ c__udpgalM |
c__udpglc c__udpgal |
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Reaction | c__UGP | UDP-glucose pyrophosphorylase [c__] | ⇆ | c__glc1p + c__utp + c__hydron ⇆ c__udpglc + c__ppi |
c__glc1pM c__udpglcM c__gal1p c__gal1pM c__udpgal c__udpgalM |
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Reaction | c__UGPM | UDP-glucose pyrophosphorylase M [c__] | ⇆ | c__glc1pM + c__utp + c__hydron ⇆ c__udpglcM + c__ppi |
c__glc1p c__udpglc c__gal1p c__gal1pM c__udpgal c__udpgalM |
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Reaction | c__UGALP | UDP-galactose pyrophosphorylase [c__] | ⇆ | c__gal1p + c__utp + c__hydron ⇆ c__udpgal + c__ppi |
c__glc1p c__glc1pM c__udpglc c__udpglcM c__gal1pM c__udpgalM |
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Reaction | c__UGALPM | UDP-galactose pyrophosphorylase M [c__] | ⇆ | c__gal1pM + c__utp + c__hydron ⇆ c__udpgalM + c__ppi |
c__glc1p c__glc1pM c__udpglc c__udpglcM c__gal1p c__udpgal |
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Reaction | c__PPASE | Pyrophosphatase [c__] | ➞ | c__ppi + c__h2o ➞ 2.0 c__phos + c__hydron | |||||
Reaction | c__NDKU | ATP:UDP phosphotransferase [c__] | ⇆ | c__atp + c__udp ⇆ c__adp + c__utp | |||||
Reaction | c__PGM1 | Phosphoglucomutase-1 [c__] | ⇆ | c__glc1p ⇆ c__glc6p |
c__glc1pM c__glc6pM |
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Reaction | c__PGM1M | Phosphoglucomutase-1 M [c__] | ⇆ | c__glc1pM ⇆ c__glc6pM |
c__glc1p c__glc6p |
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Reaction | c__GLY | Glycolysis [c__] | ⇆ | c__glc6p + 5.0 c__o2 ⇆ c__phos + 6.0 c__co2 + 5.0 c__h2o | BQB_IS
SBO:0000176 |
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Reaction | c__GLYM | Glycolysis M [c__] | ➞ | c__glc6pM + 5.0 c__o2 ➞ c__phos + 6.0 c__co2 + 5.0 c__h2o | BQB_IS
SBO:0000176 |
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Reaction | c__GTFGAL | Glycosyltransferase galactose [c__] | ➞ | c__udpgal + c__acpt ➞ c__udp + c__acptgal + c__hydron |
c__udpgalM |
BQB_IS
SBO:0000176 |
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Reaction | c__GTFGALM | Glycosyltransferase galactose M [c__] | ➞ | c__udpgalM + c__acpt ➞ c__udp + c__acptgalM + c__hydron |
c__udpgal |
BQB_IS
SBO:0000176 |
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Reaction | c__GTFGLC | Glycosyltransferase glucose [c__] | ➞ | c__udpglc + c__acpt ➞ c__udp + c__acptglc + c__hydron |
c__udpglcM |
BQB_IS
SBO:0000176 |
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Reaction | c__GTFGLCM | Glycosyltransferase glucose M [c__] | ➞ | c__udpglcM + c__acpt ➞ c__udp + c__acptglcM + c__hydron |
c__udpglc |
BQB_IS
SBO:0000176 |
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Reaction | e__H2OTM | H2O M transport [e__] | ⇆ | e__h2oM ⇆ h__h2oM | BQB_IS
SBO:0000185 |
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Reaction | e__GLUT2_GAL | galactose transport [e__] | ⇆ | e__gal ⇆ c__gal |
e__galM c__galM |
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Reaction | e__GLUT2_GALM | galactose transport M [e__] | ⇆ | e__galM ⇆ c__galM |
e__gal c__gal |