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About the Solvent Guide

❰ Return to Solvent Guide

Solvent flash cards were created using the information provided by CHEM21 and an industry solvent substitution guide. This tool is intended only as a guide to allow the user to think about different aspects of solvent sustainable.

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Solvent Name
CHEM21 Hazard Rating
CAS# XXX-XX-X
Family* Solvent Class
Boiling Point / °C* BP
Flash Point / °C* FP
Safety* e.g. 8
Health* e.g. 3
Environment* e.g. 5
Worst H3xx* e.g. H304🛈
Worst H4xx* e.g. H411🛈

Issues:^ Justification for substitution
Possible Substitution(s):^


Notes:

There are four CHEM21 hazard rating categories: Recommended, Problematic, Hazardous, and Highly Hazardous. Default ranking was determined from the Safety, Health, and Environmental scores. These ratings were updated after discussion leading to the fourth Highly Hazardous category. Cards are coloured to this overall rating. In this example, the overall rating of Hazardous is shown by the red border.

#CAS codes were collected from PubChem. The CAS code is linked to the corresponding page on PubChem.

*This data was provided by CHEM21.[1] See the CHEM21 publications for details on how individual Safety, Health, and Environment ratings were calculated. The radar plot also shows this data. The worst H3xx and H4xx are shown. Be aware that there may be other hazards associated with the solvent.

^This data is from an industry substitution guide.[2] This is purely to illustrate a potential issue with a solvent and how an alternative solvent may be more appropriate.

References:

[1] CHEM21 selection guide of classical- and less classical-solvents Green Chem., 2016, 18, 288-296.

[2] Green chemistry tools to influence a medicinal chemistry and research chemistry based organisation Green Chem., 2008, 10, 31-36.

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