{{ title }}

Generated by OpenPKFlow • {{ generated_at }}

{% if warnings %}
Warnings:
{% endif %}
N Observed
{{ n_obs }}
N Replicates
{{ n_replicates }}
N Bins
{{ n_bins }}
Percentiles
{{ pi_lo }}/{{ pi_med }}/{{ pi_hi }}

Visual Predictive Check

VPC plot

VPC Band Data

{% for i in range(bin_mids | length) %} {% endfor %}
Bin Mid Obs {{ pi_lo }}thObs {{ pi_med }}thObs {{ pi_hi }}th Sim {{ pi_lo }}thSim {{ pi_med }}thSim {{ pi_hi }}th
{{ "%.2f" | format(bin_mids[i]) }} {{ "%.3g" | format(obs_lower[i]) if obs_lower[i] == obs_lower[i] else "---" }} {{ "%.3g" | format(obs_median[i]) if obs_median[i] == obs_median[i] else "---" }} {{ "%.3g" | format(obs_upper[i]) if obs_upper[i] == obs_upper[i] else "---" }} {{ "%.3g" | format(sim_lower[i]) if sim_lower[i] == sim_lower[i] else "---" }} {{ "%.3g" | format(sim_median[i]) if sim_median[i] == sim_median[i] else "---" }} {{ "%.3g" | format(sim_upper[i]) if sim_upper[i] == sim_upper[i] else "---" }}

This report was generated using OpenPKFlow (open-source). VPC bands are computed from simulation replicates using the supplied model and dosing regimen with proportional residual variability. Final regulatory interpretation should be reviewed by qualified experts.