Metadata-Version: 2.4
Name: agitation
Version: 0.0.2
Summary: Deep Learning based tool to quantify subject motion in T1w brain MRI
Project-URL: Repository, https://github.com/chbricout/agitation
Author-email: Charles Bricout <bricout.charles@outlook.com>
License-Expression: MIT
License-File: LICENSE
Requires-Python: >=3.11
Requires-Dist: click==8.1.8
Requires-Dist: dotenv==0.9.9
Requires-Dist: monai==1.4.0
Requires-Dist: nibabel==5.3.2
Requires-Dist: pandas==2.2.3
Requires-Dist: platformdirs==4.3.7
Requires-Dist: requests==2.32.3
Requires-Dist: rich==14.0.0
Requires-Dist: torch==2.7.0
Requires-Dist: tqdm==4.67.1
Description-Content-Type: text/markdown

# Agitation

This repository presents a deep learning-based tool to quantify subject motion in T1-weighted brain MRI.  
The model used by this tool can be trained using our [research code](https://github.com/chbricout/cortical-motion).

## Getting Started

### Installation

You will need an environment with at least **Python 3.11**. Then run:

```bash
pip install agitation
```

Alternatively, you can clone the repository and use:

```bash
python cli.py
```

instead of `agitation`.

### Setup

#### Model

We use a TorchScript version of our best model.  
All model checkpoints and the final TorchScript file are available on [Zenodo](https://zenodo.org/records/15288225).

The model will be downloaded automatically when needed. However, you can also manually download it with:

```bash
agitation manage check
```

The model is stored in your application data directory. You can retrieve the exact location using the `check` command.

To remove all downloaded data:

```bash
agitation manage delete
```

#### MRI Data

Our model was trained on data preprocessed with Clinica's [T1-linear](https://aramislab.paris.inria.fr/clinica/docs/public/dev/Pipelines/T1_Linear/) pipeline.  
While it may work with any T1-weighted MRI, we **strongly recommend** using the same preprocessing pipeline to ensure consistent results.

### CLI Usage

#### Full Dataset

To quantify motion on a full dataset, use the command:

```bash
agitation dataset
```

##### Arguments:

- `-d, --dataset`: Path to the root of the dataset. It must be organized according to BIDS or CAPS (Clinica) standards and contain either an `anat` folder or `t1_linear` for CAPS.
- `-f, --file`: Path to a CSV file describing the data to process. The file must contain at least a `data` column specifying the path to each volume. Other columns will be copied to the output CSV.
- `-g, --gpu`: Flag to enable GPU inference.
- `--cuda`: Specify the GPU index to use (defaults to 0).
- `-o, --output`: Path to the output CSV file.

##### Examples:

```bash
agitation dataset --dataset <path_to_root> -g --output <path_to_output_file>
```

```bash
agitation dataset --file <path_to_csv>
```

#### Subject Level

To quantify motion at the subject level, use the command:

```bash
agitation inference
```

This entry point is recommended for use with pipeline tools like Nipoppy.

##### Arguments:

- `--bids_dir`: Path to the root of a BIDS dataset.
- `--subject_id`: Subject identifier in BIDS format: `sub-<label>`.
- `--session_id`: Session identifier in BIDS format: `ses-<label>`.
- `-g, --gpu`: Flag to enable GPU inference.
- `--cuda`: Specify the GPU index to use (defaults to 0).
- `--output_dir`: Path to the output directory.

##### Example:

```bash
agitation inference --bids_dir tests/data/bids_sub_ses --subject_id sub-000103 --session_id ses-standard --output_dir ./
```

### Container, Boutiques, and Nipoppy

Our tool offers a Boutiques descriptor, available in the `descriptors` folder, and an Apptainer container (container definition in `containers`).

To integrate our tool into a Nipoppy dataset, copy `descriptors/agitation.json` to your dataset's `pipelines/agitation-<version>/descriptor.json` and `descriptors/invocation.json` to `pipelines/agitation-<version>/invocation.json`.

### Library

The `agitation` package can also be used as a library to include motion estimation in your projects.

#### Downloading the Model

To manually download the model within your code:

```python
from agitation.data_manager import download_model

download_model()
```

#### Dataloader Inference

To run inference on a dataloader:

```python
from monai.data.dataset import Dataset
from torch.utils.data import DataLoader

from agitation.inference import estimate_motion_dl
from agitation.processing import LoadVolume

# Example usage
dataset = Dataset(<your_data_as_a_dict>, transform=LoadVolume())
dataloader = DataLoader(dataset)
estimate_motion_dl(dataloader, cuda=0)
```

#### Batch Inference

To perform inference on a single batch:

```python
import torch

from agitation.config import MODEL_PATH
from agitation.processing import SoftLabelToPred

# Dataloading, cropping, and normalization steps

model = torch.jit.load(
    MODEL_PATH,
    map_location="cuda:0"  # If using CUDA
)
converter = SoftLabelToPred()

with torch.inference_mode():
    prediction = model(data).cpu()
    motions = converter(prediction)
```

## Contributing

### Setup

Once the repository is cloned, install the development dependencies with:

```bash
pip install -r dev_requirements.txt
```

### Tests

#### Test Tools

We use:

- `pytest` for unit tests
- `pytest-cov` for coverage reports (targeting 100% test coverage)

Run tests via:

```bash
pytest --cov
```

Other tools:

- `ruff` for linting and formatting (automatically applied via `pre-commit`)
- Additional code quality tools: `ssort`, `pydocstyle`, `mypy`, and `pylint`

#### Test Data

All test data are extracted from MR-ART:

> Nárai, Á., Hermann, P., Auer, T. et al. Movement-related artefacts (MR-ART) dataset of matched motion-corrupted and clean structural MRI brain scans. *Sci Data* 9, 630 (2022). https://doi.org/10.1038/s41597-022-01694-8

### Deployment

To fully deploy a new version, follow these steps in order:

1. Build and deploy the PyPI package (used for the Apptainer image).
2. Build the Apptainer image and publish it to Docker Hub.
3. Publish any modifications to the Boutiques descriptor on Zenodo.

#### Python Packaging

Build the package using:

```bash
python -m build
```

Deploy to PyPI with:

```bash
twine upload dist/*
```

#### Apptainer Container

Build the container using:

```bash
apptainer build agitation.sif containers/agitation.def
```

Publish with:

```bash
apptainer push agitation.sif oras://docker.io/chbricout/agitation:latest
```

#### Boutiques Descriptor

Publish to Zenodo using:

```bash
bosh publish --sandbox -y --zenodo-token <ZENODO TOKEN> descriptors/agitation.json
```
