The model.nullspace subpackage implements the nullspace approach
introduced by Wagner (see [1], for an overview and implementation details also
[2], [3]).
References
-
Wagner, C., "Nullspace approach to determine the elementary modes of
chemical reaction systems", 2004,
J.Phys. Chem. B, 108, 2425-2431.
-
Gagneur, J. and Klamt, S., "Computation of elementary modes: A unifying
framework and the new binary approach", 2004,
BMC Bioinformatics, 5, 175.
- Terzer, M. and Stelling, J., "Large scale computation of elementary flux
modes with bit pattern trees",
Bioinformatics, August 1, 2008,
doi:10.1093/bioinformatics/btn401