Protein Natural Host Normal Function Prion State Prion Phenotype Year Identified
Ure2p Saccharomyces cerevisiae Nitrogen catabolite repressor [URE3] Growth on poor nitrogen sources 1994
Sup35p Saccharomyces cerevisiae Translation termination factor [PSI+] Increased levels of nonsense suppression 1994
HET-S Podospora anserina Regulates heterokaryon incompatibility [Het-s] Heterokaryon formation between incompatible strains 1997
vacuolar protease B Saccharomyces cerevisiae death in stationary phase, failure in meiosis [β] failure to degrade cellular proteins under N starvation 2003
MAP kinases Podospora anserina increased pigment, slow growth [C] 2006
Rnq1p Saccharomyces cerevisiae Protein template factor [RNQ+],[PIN+] Promotes aggregation of other prions 2008
Mca1* Saccharomyces cerevisiae Putative Yeast Caspase [MCA+] Unknown 2008
Swi1 Saccharomyces cerevisiae Chromatin remodeling [SWI+] Poor growth on some carbon sources 2008
Cyc8 Saccharomyces cerevisiae Transcriptional repressor [OCT+] Transcriptional derepression of multiple genes 2009
Mot3 Saccharomyces cerevisiae Nuclear transcription factor [MOT3+] Transcriptional derepression of anaerobic genes 2009
Pma1+Std1 [17] Saccharomyces cerevisiae Pma1 = major plasma membrane proton pump, Std1=minor pump [GAR+] Resistant to glucose-associated repression 2009
Sfp1 [18] Saccharomyces cerevisiae Global transcriptional regulator [ISP+] Antisuppressor of certain sup35 mutations 2010
Mod5 [19] Saccharomyces cerevisiae [MOD+] 2012