Portrait Name From Until Relationship with predecessor
Cosimo di Medici (Bronzino).jpg Cosimo de' Medici
(Pater Patriae)
1434 1 August 1464 Son of Giovanni di Bicci de' Medici who was not as prominently involved in Florentine politics, rather more involved in the financial area.
Piero di Cosimo de' Medici.jpg Piero I de' Medici
(Piero the Gouty)
1 August 1464 2 December 1469 Eldest son of Cosimo de' Medici.
Lorenzo de Medici.jpg Lorenzo I de' Medici
(Lorenzo the Magnificent)
2 December 1469 9 April 1492 Eldest son of Piero I de' Medici.
Agnolo Bronzino - Piero il Fatuo.jpg Piero II de' Medici
(Piero the Unfortunate)
9 April 1492 8 November 1494 Eldest son of Lorenzo the Magnificent. Overthrown when Charles VIII of France invaded as a full republic was restored, first under the theocracy of Girolamo Savonarola and then statesman Piero Soderini.
Cardinal Giovanni de' Medici.jpg Cardinal Giovanni de' Medici 31 August 1512 9 March 1513 Brother of Piero the Unfortunate, second son of Lorenzo the Magnificent. Elected to the Papacy, becoming Pope Leo X.
Giuliano de' Medici duca di Nemours.jpg Giuliano de' Medici, Duke of Nemours 9 March 1513 17 March 1516 Brother of Cardinal Giovanni de' Medici, third son of Lorenzo the Magnificent.
Duke-Lorenzo.jpg Lorenzo II de' Medici, Duke of Urbino 17 March 1516 4 May 1519 Nephew of Giuliano de' Medici, Duke of Nemours, son of Piero the Unfortunate.
Portrait of Giulio de Medici (1478 - 1534) Pope Clement VII.jpg Cardinal Giulio de' Medici 4 May 1519 19 November 1523 Cousin of Lorenzo II de' Medici, Duke of Urbino, son of Giuliano de' Medici who was the brother of Lorenzo the Magnificent. Elected to the Papacy, becoming Pope Clement VII.
Ippolito de' Medici.jpg Cardinal Ippolito de' Medici 19 November 1523 24 October 1529 Cousin of Cardinal Giulio de' Medici, illegitimate son of Giuliano de' Medici, Duke of Nemours.