Internal loop free energies:

initiation
4	1.1
5	2.0
6	2.0

Asymmetry
0.6

AU/GU closure:
0.7

2x3 terminal mismatch:
YR/AG -0.5
RY/GA -1.2
YR/GA -1.1
GG -0.8
UU -0.4

Other terminal mismatch:
AG -0.8
GA -1.0
GG -1.2
UU -0.7
