Clinical Trial Finder Report

Query: BRCA1 breast cancer
Generated: 2026-03-19T16:48:46+00:00
Trials found: 20 (5 recruiting)

Trials

Metric	Value
Total trials	20
Recruiting now	5

COMPLETED Registry of Mastectomy for Breast Cancer Risk Reduction

NCT00555503 | Phase: N/A | 2007-11 -- 2014-01

Quality of Life, Mastectomy, Breast Neoplasms

RECRUITING Pancreatic Cancer Genetics

NCT01102569 | Phase: N/A | 2008-01 -- 2027-12

Pancreatic Cancer

ACTIVE_NOT_RECRUITING Niraparib + Dostarlimab In BRCA Mutated Breast Cancer

NCT04584255 | Phase: PHASE2 | 2020-12-18 -- 2029-07-17

Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer

UNKNOWN Abbreviated Breast MRI for Second Breast Cancer Detection in Women With BRCA Mutation Testing

NCT03475979 | Phase: N/A | 2018-05-01 -- 2022-06

Breast Cancer, BRCA1 Mutation, BRCA2 Mutation

COMPLETED Randomized CT to Evaluate Efficacy of Neoadjuvant Chemotherapy Customized by Levels of BRCA1-HER2 Negative Breast Cancer

NCT02365805 | Phase: PHASE2 | 2014-04 -- 2016-10-10

Breast Cancer

UNKNOWN A Study of Fluzoparib±Apatinib Versus Chemotherapy Treatment of Physician's Choice in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation

NCT04296370 | Phase: PHASE3 | 2020-07-13 -- 2025-06-30

Treatment in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation

COMPLETED Use of Recombinant hCG to Prevent Breast Cancer in BRCA1 and BRCA2 Carriers

NCT03495609 | Phase: PHASE4 | 2016-02-17 -- 2018-12-18

hCG, BRCA1 Mutation, BRCA2 Mutation

RECRUITING SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

NCT04150042 | Phase: PHASE1 | 2021-01-13 -- 2028-12

Pancreatic Adenocarcinoma Metastatic, BRCA1 Mutation, BRCA2 Mutation

RECRUITING Serum Biomarkers to Characterize the Effects of Therapy on Ovarian Reserve in Premenopausal Women With Early-stage Breast Cancer or BRCA Mutations

NCT00823654 | Phase: N/A | 2009-01 -- 2027-01

Breast Cancer

UNKNOWN Breast Cancer After Ovarian Cancer During and/or After Therapy: Genomic Evaluation

NCT05763472 | Phase: N/A | 2022-03-01 -- 2023-06-01

BRCA-Associated Breast Carcinoma

COMPLETED Phase I of Carboplatin-Olaparib Followed by Olaparib Monotherapy in Advanced Cancer

NCT02418624 | Phase: PHASE1 | 2015-05 -- 2019-01

Breast Cancer, Ovarian Cancer, Advanced Cancer

UNKNOWN Study of Quality of Life Post Salpingo-oophorectomy in BRCA1/2 & PALB2 Mutation Carriers (BRCA-HRT)

NCT05409222 | Phase: N/A | 2020-03-12 -- 2023-10

Hereditary Breast and Ovarian Cancer

COMPLETED Study Evaluating Efficacy And Tolerability Of Veliparib in Combination With Temozolomide (TMZ) or In Combination With Carboplatin and Paclitaxel Versus Placebo in Participants With Breast Cancer Gene (BRCA)1 and BRCA2 Mutation and Metastatic Breast Cancer

NCT01506609 | Phase: PHASE2 | 2012-01-23 -- 2020-09-02

Metastatic Breast Cancer

UNKNOWN Studying Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers

NCT00897455 | Phase: N/A | 2008-04 -- ?

brca1 Mutation Carrier, brca2 Mutation Carrier, Breast Cancer

ACTIVE_NOT_RECRUITING Genetic Risk Estimations for Influencing Decision Making in Women at High Risk of Breast Cancer, GENRE 2 Study

NCT04474834 | Phase: N/A | 2019-10-17 -- 2029-12-15

Breast Cancer

RECRUITING MEASUREMENT OF CIRCULATING MUTATION BURDEN

NCT06792721 | Phase: N/A | 2025-07-04 -- 2027-12-30

Breast Carcinoma, Genetic Predisposition to Cancer, BRCA Mutation

RECRUITING Novel Neoadjuvant and Adjuvant Strategy for Germline BRCA 1/2 Mutated Triple Negative Breast Cancer

NCT05485766 | Phase: PHASE2 | 2024-07-16 -- 2028-09-30

Triple Negative Breast Neoplasms, Triple Negative Breast Cancer, Breast Neoplasms

NO_LONGER_AVAILABLE Expanded Access With ABT-888 (Veliparib) to Treat Metastatic Breast Cancer

NCT02985658 | Phase: N/A | ? -- ?

Metastatic Breast Cancer With BRCA 1 or BRCA 2 Genetic Mutation, Triple-Negative Breast Cancer

ENROLLING_BY_INVITATION Strategy for Management of Patients With Hereditary Cancer Syndromes (HCS) in a Rural Environment

NCT07381985 | Phase: NA | 2023-12-29 -- 2027-12-01

Hereditary Cancer Syndromes, BRCA1 Hereditary Breast and Ovarian Cancer Syndrome, Lynch Syndrome

TERMINATED A Phase III Trial of Niraparib Versus Physician's Choice in HER2 Negative, Germline BRCA Mutation-positive Breast Cancer Patients

NCT01905592 | Phase: PHASE3 | 2014-02-25 -- 2021-10-26

Neoplasms, Breast, Carcinoma of Breast, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

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