OpenPKFlow — Bayesian Bioequivalence (2×2 Crossover)

{{ title }}

Metric{{ result.metric }}
Subjects{{ result.n_subjects }}
MCMC Samples{{ result.n_samples }}
Versionv{{ version }}
Bioequivalence Decision
{{ "%.3f"|format(result.p_be) }}
P(0.{{ be_lo|int * 100 }}0 ≤ GMR ≤ 1.25)
Bayesian Decision
{{ be_verdict }}
GMR: {{ fmt(result.gmr_mean) }}   [95% CrI: {{ fmt(result.gmr_95ci[0]) }}, {{ fmt(result.gmr_95ci[1]) }}]
log(GMR): {{ fmt(result.beta_t_mean) }}   [95% CrI: {{ fmt(result.beta_t_95ci[0]) }}, {{ fmt(result.beta_t_95ci[1]) }}]
{% if result.warnings %}
Diagnostic Warnings
    {% for w in result.warnings %}
  • {{ w }}
    • {% endfor %}
{% endif %}
Bayesian vs Frequentist Comparison
AnalysisGMRLowerUpperDecision
Bayesian (95% CrI) {{ fmt(result.gmr_mean) }} {{ fmt(result.gmr_95ci[0]) }} {{ fmt(result.gmr_95ci[1]) }} P(BE) = {{ "%.3f"|format(result.p_be) }}
Frequentist (90% CI) {{ fmt(result.freq_gmr) }} {{ fmt(result.freq_90ci[0]) }} {{ fmt(result.freq_90ci[1]) }} {{ freq_be_str }}
Variance Components (Posterior Means)
Between-Subject SD
{{ fmt(result.sigma_b_mean) }}
Within-Subject SD
{{ fmt(result.sigma_w_mean) }}
CV% (intra, approx)
{{ "%.1f"|format((result.sigma_w_mean ** 2) ** 0.5 * 100) }}%
GMR Posterior Distribution
GMR Posterior
Disclaimer: {{ disclaimer }}