Coverage for cc_modules/cc_snomed.py: 60%
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1r"""
2camcops_server/cc_modules/cc_snomed.py
4===============================================================================
6 Copyright (C) 2012, University of Cambridge, Department of Psychiatry.
7 Created by Rudolf Cardinal (rnc1001@cam.ac.uk).
9 This file is part of CamCOPS.
11 CamCOPS is free software: you can redistribute it and/or modify
12 it under the terms of the GNU General Public License as published by
13 the Free Software Foundation, either version 3 of the License, or
14 (at your option) any later version.
16 CamCOPS is distributed in the hope that it will be useful,
17 but WITHOUT ANY WARRANTY; without even the implied warranty of
18 MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
19 GNU General Public License for more details.
21 You should have received a copy of the GNU General Public License
22 along with CamCOPS. If not, see <https://www.gnu.org/licenses/>.
24===============================================================================
26**CamCOPS code to support SNOMED-CT.**
28Note that the licensing arrangements for SNOMED-CT mean that the actual codes
29must be separate (and not part of the CamCOPS code). See the documentation.
31Some tests:
33.. code-block:: python
35 import logging
36 from cardinal_pythonlib.logs import main_only_quicksetup_rootlogger
37 from camcops_server.cc_modules.cc_request import get_command_line_request
38 from camcops_server.cc_modules.cc_snomed import *
39 from camcops_server.tasks.phq9 import Phq9
40 main_only_quicksetup_rootlogger(level=logging.DEBUG)
41 req = get_command_line_request()
43 # ---------------------------------------------------------------------
44 # Read the XML, etc.
45 # ---------------------------------------------------------------------
47 print(VALID_SNOMED_LOOKUPS)
48 concepts = get_all_snomed_concepts(req.config.snomed_xml_filename)
50 # ---------------------------------------------------------------------
51 # Test a task, and loading SNOMED data from XML via the CamCOPS config
52 # ---------------------------------------------------------------------
54 phq9 = Phq9()
55 print("\n".join(str(x) for x in phq9.get_snomed_codes(req)))
56 phq9.q1 = 2
57 phq9.q2 = 2
58 phq9.q3 = 2
59 phq9.q4 = 2
60 phq9.q5 = 2
61 phq9.q6 = 2
62 phq9.q7 = 2
63 phq9.q8 = 2
64 phq9.q9 = 2
65 phq9.q10 = 2
66 print("\n".join(repr(x) for x in phq9.get_snomed_codes(req)))
67 print("\n".join(str(x) for x in phq9.get_snomed_codes(req)))
69Note diagnostic coding maps:
71- https://www.nlm.nih.gov/research/umls/mapping_projects/icd9cm_to_snomedct.html
72- https://www.nlm.nih.gov/research/umls/mapping_projects/snomedct_to_icd10cm.html
74Other testing:
76.. code-block:: bash
78 camcops_server dev_cli --verbose
80.. code-block:: python
82 from camcops_server.cc_modules.cc_snomed import *
84 athena_concepts = get_athena_concepts(config.athena_concept_tsv_filename)
85 relationships = get_athena_concept_relationships(config.athena_concept_relationship_tsv_filename)
86 rel_ids = set(r.relationship_id for r in relationships)
87 icd9, icd10 = get_icd9cm_icd10_snomed_concepts(config.athena_concept_tsv_filename, config.athena_concept_relationship_tsv_filename)
89 ac = get_athena_concepts(config.athena_concept_tsv_filename, vocabulary_ids=[AthenaVocabularyId.SNOMED], concept_codes=["4303690"])
91Regarding temporal coding:
93- SNOMED CT has some concepts relating to time (e.g. "time aspect", "single
94 point in time", "date of birth", "date of event", "time (property)", "time
95 (attribute)"). HOWEVER, note that SNOMED-CT isn't intended for recording
96 event dates:
98 - https://confluence.ihtsdotools.org/display/DOCRSG/3.5.+Safely+representing+the+context+of+recorded+codes
100 "Contextual information that is not represented by SNOMED CT
102 Clinical statements that contain SNOMED CT Concept representations will
103 be associated with some information which is not intended to be
104 represented using SNOMED CT:
106 - Dates, times of an activity of recording and activity;
107 - Quantitative information including ranges and durations;
108 - Identifiers or names of authors, providers of information or other
109 parties involved in a recorded activity.
110 - SNOMED CT is not intended to represent this information. Appropriate
111 constructs in a standardized or proprietary record architecture
112 should be used to relate this information to SNOMED CT encoded
113 clinical statements."
115 - https://confluence.ihtsdotools.org/display/DOCRSG/3.4.+Record+architectures%2C+structures+and+semantics
117 "Using SNOMED CT in standard architectures
119 ...
121 Each health record component has the potential to include:
123 - Dates and times of actual and planned events.
124 - Associations with people, organizations, devices and other entities
125 that participate or are used in relations to a recorded event or
126 plan.
127 - Codes or other representations that name or provide the semantic
128 information container, link, or statement:
130 - SNOMED CT fulfills this role in a structured health record.
132 - Additional data including text, numeric values, images and other
133 digital data."
135- That explains why the grammar has no explanation of how to represent
136 dates/times, perhaps!
138""" # noqa
140from collections import OrderedDict
141import csv
142import logging
143from typing import Dict, List, Optional, Set, Tuple, Union
144import xml.etree.cElementTree as ElementTree
146from cardinal_pythonlib.athena_ohdsi import (
147 AthenaConceptRow,
148 AthenaRelationshipId,
149 AthenaVocabularyId,
150 get_athena_concept_relationships,
151 get_athena_concepts,
152)
153from cardinal_pythonlib.logs import BraceStyleAdapter
154from cardinal_pythonlib.reprfunc import simple_repr
156# noinspection PyUnresolvedReferences
157from cardinal_pythonlib.snomed import ( # noqa: F401
158 SnomedAttribute,
159 SnomedAttributeGroup,
160 SnomedAttributeSet,
161 SnomedConcept as SnomedConceptCardinalPythonlib,
162 SnomedExpression as SnomedExpressionCardinalPythonlib,
163 SnomedFocusConcept,
164 SnomedRefinement,
165 SnomedValue,
166)
168from camcops_server.cc_modules.cc_cache import cache_region_static, fkg
169from camcops_server.cc_modules.cc_xml import XmlDataTypes, XmlElement
171log = BraceStyleAdapter(logging.getLogger(__name__))
174# =============================================================================
175# Constants
176# =============================================================================
178# -----------------------------------------------------------------------------
179# Internal
180# -----------------------------------------------------------------------------
182SNOMED_XML_NAME = "snomed_ct_expression"
184# -----------------------------------------------------------------------------
185# ICD-9-CM; from the client: camcops --print_icd9_codes
186# -----------------------------------------------------------------------------
188CLIENT_ICD9CM_CODES = set(
189 """
190290.0 290.1 290.10 290.11 290.12 290.13 290.2 290.20 290.21 290.3 290.4 290.40
191290.41 290.42 290.43 290.8 290.9 291.0 291.1 291.2 291.3 291.4 291.5 291.8
192291.81 291.82 291.89 291.9 292.0 292.1 292.11 292.12 292.2 292.8 292.81 292.82
193292.83 292.84 292.85 292.89 292.9 293.0 293.1 293.8 293.81 293.82 293.83 293.84
194293.89 293.9 294.0 294.1 294.10 294.11 294.2 294.20 294.21 294.8 294.9 295.0
195295.00 295.01 295.02 295.03 295.04 295.05 295.1 295.10 295.11 295.12 295.13
196295.14 295.15 295.2 295.20 295.21 295.22 295.23 295.24 295.25 295.3 295.30
197295.31 295.32 295.33 295.34 295.35 295.4 295.40 295.41 295.42 295.43 295.44
198295.45 295.5 295.50 295.51 295.52 295.53 295.54 295.55 295.6 295.60 295.61
199295.62 295.63 295.64 295.65 295.7 295.70 295.71 295.72 295.73 295.74 295.75
200295.8 295.80 295.81 295.82 295.83 295.84 295.85 295.9 295.90 295.91 295.92
201295.93 295.94 295.95 296.0 296.00 296.01 296.02 296.03 296.04 296.05 296.06
202296.1 296.10 296.11 296.12 296.13 296.14 296.15 296.16 296.2 296.20 296.21
203296.22 296.23 296.24 296.25 296.26 296.3 296.30 296.31 296.32 296.33 296.34
204296.35 296.36 296.4 296.40 296.41 296.42 296.43 296.44 296.45 296.46 296.5
205296.50 296.51 296.52 296.53 296.54 296.55 296.56 296.6 296.60 296.61 296.62
206296.63 296.64 296.65 296.66 296.7 296.8 296.80 296.81 296.82 296.89 296.9
207296.90 296.99 297.0 297.1 297.2 297.3 297.8 297.9 298.0 298.1 298.2 298.3 298.4
208298.8 298.9 299.0 299.00 299.01 299.1 299.10 299.11 299.8 299.80 299.81 299.9
209299.90 299.91 300.0 300.00 300.01 300.02 300.09 300.1 300.10 300.11 300.12
210300.13 300.14 300.15 300.16 300.19 300.2 300.20 300.21 300.22 300.23 300.29
211300.3 300.4 300.5 300.6 300.7 300.8 300.81 300.82 300.89 300.9 301.0 301.1
212301.10 301.11 301.12 301.13 301.2 301.20 301.21 301.22 301.3 301.4 301.5 301.50
213301.51 301.59 301.6 301.7 301.8 301.81 301.82 301.83 301.84 301.89 301.9 302.0
214302.1 302.2 302.3 302.4 302.5 302.50 302.51 302.52 302.53 302.6 302.7 302.70
215302.71 302.72 302.73 302.74 302.75 302.76 302.79 302.8 302.81 302.82 302.83
216302.84 302.85 302.89 302.9 303.0 303.00 303.01 303.02 303.03 303.0x 303.9
217303.90 303.91 303.92 303.93 304.0 304.00 304.01 304.02 304.03 304.1 304.10
218304.11 304.12 304.13 304.2 304.20 304.21 304.22 304.23 304.3 304.30 304.31
219304.32 304.33 304.4 304.40 304.41 304.42 304.43 304.5 304.50 304.51 304.52
220304.53 304.6 304.60 304.61 304.62 304.63 304.7 304.70 304.71 304.72 304.73
221304.8 304.80 304.81 304.82 304.83 304.9 304.90 304.91 304.92 304.93 305.0
222305.00 305.01 305.02 305.03 305.0x 305.1 305.10 305.11 305.12 305.13 305.2
223305.20 305.21 305.22 305.23 305.2x 305.3 305.30 305.31 305.32 305.33 305.3x
224305.4 305.40 305.41 305.42 305.43 305.4x 305.5 305.50 305.51 305.52 305.53
225305.5x 305.6 305.60 305.61 305.62 305.63 305.6x 305.7 305.70 305.71 305.72
226305.73 305.7x 305.8 305.80 305.81 305.82 305.83 305.8x 305.9 305.90 305.91
227305.92 305.93 305.9x 306.0 306.1 306.2 306.3 306.4 306.50 306.51 306.52 306.53
228306.59 306.6 306.7 306.8 306.9 307.0 307.1 307.2 307.20 307.21 307.22 307.23
229307.3 307.4 307.40 307.41 307.42 307.43 307.44 307.45 307.46 307.47 307.48
230307.49 307.5 307.50 307.51 307.52 307.53 307.54 307.59 307.6 307.7 307.8 307.80
231307.81 307.89 307.9 308.0 308.1 308.2 308.3 308.4 308.9 309.0 309.1 309.2
232309.21 309.22 309.23 309.24 309.28 309.29 309.3 309.4 309.8 309.81 309.82
233309.83 309.89 309.9 310.0 310.1 310.2 310.8 310.81 310.89 310.9 311 312.0
234312.00 312.01 312.02 312.03 312.1 312.10 312.11 312.12 312.13 312.2 312.20
235312.21 312.22 312.23 312.3 312.30 312.31 312.32 312.33 312.34 312.35 312.39
236312.4 312.8 312.81 312.82 312.89 312.9 313.0 313.1 313.2 313.21 313.22 313.23
237313.3 313.8 313.81 313.82 313.83 313.89 313.9 314.0 314.00 314.01 314.1 314.2
238314.8 314.9 315.0 315.00 315.01 315.02 315.09 315.1 315.2 315.3 315.31 315.32
239315.34 315.35 315.39 315.4 315.5 315.8 315.9 316 317 318.0 318.1 318.2 319
240V71.09
241""".split()
242)
244# -----------------------------------------------------------------------------
245# ICD-10; from the client: camcops --print_icd10_codes
246# -----------------------------------------------------------------------------
248CLIENT_ICD10_CODES = set(
249 """
250F00 F00.0 F00.00 F00.000 F00.001 F00.002 F00.01 F00.010 F00.011 F00.012 F00.02
251F00.020 F00.021 F00.022 F00.03 F00.030 F00.031 F00.032 F00.04 F00.040 F00.041
252F00.042 F00.1 F00.10 F00.100 F00.101 F00.102 F00.11 F00.110 F00.111 F00.112
253F00.12 F00.120 F00.121 F00.122 F00.13 F00.130 F00.131 F00.132 F00.14 F00.140
254F00.141 F00.142 F00.2 F00.20 F00.200 F00.201 F00.202 F00.21 F00.210 F00.211
255F00.212 F00.22 F00.220 F00.221 F00.222 F00.23 F00.230 F00.231 F00.232 F00.24
256F00.240 F00.241 F00.242 F00.9 F00.90 F00.900 F00.901 F00.902 F00.91 F00.910
257F00.911 F00.912 F00.92 F00.920 F00.921 F00.922 F00.93 F00.930 F00.931 F00.932
258F00.94 F00.940 F00.941 F00.942 F01 F01.0 F01.00 F01.000 F01.001 F01.002 F01.01
259F01.010 F01.011 F01.012 F01.02 F01.020 F01.021 F01.022 F01.03 F01.030 F01.031
260F01.032 F01.04 F01.040 F01.041 F01.042 F01.1 F01.10 F01.100 F01.101 F01.102
261F01.11 F01.110 F01.111 F01.112 F01.12 F01.120 F01.121 F01.122 F01.13 F01.130
262F01.131 F01.132 F01.14 F01.140 F01.141 F01.142 F01.2 F01.20 F01.200 F01.201
263F01.202 F01.21 F01.210 F01.211 F01.212 F01.22 F01.220 F01.221 F01.222 F01.23
264F01.230 F01.231 F01.232 F01.24 F01.240 F01.241 F01.242 F01.3 F01.30 F01.300
265F01.301 F01.302 F01.31 F01.310 F01.311 F01.312 F01.32 F01.320 F01.321 F01.322
266F01.33 F01.330 F01.331 F01.332 F01.34 F01.340 F01.341 F01.342 F01.8 F01.80
267F01.800 F01.801 F01.802 F01.81 F01.810 F01.811 F01.812 F01.82 F01.820 F01.821
268F01.822 F01.83 F01.830 F01.831 F01.832 F01.84 F01.840 F01.841 F01.842 F01.9
269F01.90 F01.900 F01.901 F01.902 F01.91 F01.910 F01.911 F01.912 F01.92 F01.920
270F01.921 F01.922 F01.93 F01.930 F01.931 F01.932 F01.94 F01.940 F01.941 F01.942
271F02 F02.0 F02.00 F02.000 F02.001 F02.002 F02.01 F02.010 F02.011 F02.012 F02.02
272F02.020 F02.021 F02.022 F02.03 F02.030 F02.031 F02.032 F02.04 F02.040 F02.041
273F02.042 F02.1 F02.10 F02.100 F02.101 F02.102 F02.11 F02.110 F02.111 F02.112
274F02.12 F02.120 F02.121 F02.122 F02.13 F02.130 F02.131 F02.132 F02.14 F02.140
275F02.141 F02.142 F02.2 F02.20 F02.200 F02.201 F02.202 F02.21 F02.210 F02.211
276F02.212 F02.22 F02.220 F02.221 F02.222 F02.23 F02.230 F02.231 F02.232 F02.24
277F02.240 F02.241 F02.242 F02.3 F02.30 F02.300 F02.301 F02.302 F02.31 F02.310
278F02.311 F02.312 F02.32 F02.320 F02.321 F02.322 F02.33 F02.330 F02.331 F02.332
279F02.34 F02.340 F02.341 F02.342 F02.4 F02.40 F02.400 F02.401 F02.402 F02.41
280F02.410 F02.411 F02.412 F02.42 F02.420 F02.421 F02.422 F02.43 F02.430 F02.431
281F02.432 F02.44 F02.440 F02.441 F02.442 F02.8 F02.80 F02.800 F02.801 F02.802
282F02.81 F02.810 F02.811 F02.812 F02.82 F02.820 F02.821 F02.822 F02.83 F02.830
283F02.831 F02.832 F02.84 F02.840 F02.841 F02.842 F03 F03.0 F03.00 F03.000 F03.001
284F03.002 F03.01 F03.010 F03.011 F03.012 F03.02 F03.020 F03.021 F03.022 F03.03
285F03.030 F03.031 F03.032 F03.04 F03.040 F03.041 F03.042 F04 F05 F05.0 F05.1
286F05.8 F05.9 F06 F06.0 F06.1 F06.2 F06.3 F06.4 F06.5 F06.6 F06.7 F06.8 F06.9 F07
287F07.0 F07.1 F07.2 F07.8 F07.9 F09 F10 F10.0 F10.00 F10.01 F10.02 F10.03 F10.04
288F10.05 F10.06 F10.07 F10.1 F10.2 F10.20 F10.200 F10.201 F10.202 F10.21 F10.22
289F10.23 F10.24 F10.241 F10.242 F10.25 F10.26 F10.3 F10.30 F10.31 F10.4 F10.40
290F10.41 F10.5 F10.50 F10.51 F10.52 F10.53 F10.54 F10.55 F10.56 F10.6 F10.7
291F10.70 F10.71 F10.72 F10.73 F10.74 F10.75 F10.8 F10.9 F11 F11.0 F11.00 F11.01
292F11.02 F11.03 F11.04 F11.05 F11.06 F11.1 F11.2 F11.20 F11.200 F11.201 F11.202
293F11.21 F11.22 F11.23 F11.24 F11.241 F11.242 F11.25 F11.26 F11.3 F11.30 F11.31
294F11.4 F11.40 F11.41 F11.5 F11.50 F11.51 F11.52 F11.53 F11.54 F11.55 F11.56
295F11.6 F11.7 F11.70 F11.71 F11.72 F11.73 F11.74 F11.75 F11.8 F11.9 F12 F12.0
296F12.00 F12.01 F12.02 F12.03 F12.04 F12.05 F12.06 F12.1 F12.2 F12.20 F12.200
297F12.201 F12.202 F12.21 F12.22 F12.23 F12.24 F12.241 F12.242 F12.25 F12.26 F12.3
298F12.30 F12.31 F12.4 F12.40 F12.41 F12.5 F12.50 F12.51 F12.52 F12.53 F12.54
299F12.55 F12.56 F12.6 F12.7 F12.70 F12.71 F12.72 F12.73 F12.74 F12.75 F12.8 F12.9
300F13 F13.0 F13.00 F13.01 F13.02 F13.03 F13.04 F13.05 F13.06 F13.1 F13.2 F13.20
301F13.200 F13.201 F13.202 F13.21 F13.22 F13.23 F13.24 F13.241 F13.242 F13.25
302F13.26 F13.3 F13.30 F13.31 F13.4 F13.40 F13.41 F13.5 F13.50 F13.51 F13.52
303F13.53 F13.54 F13.55 F13.56 F13.6 F13.7 F13.70 F13.71 F13.72 F13.73 F13.74
304F13.75 F13.8 F13.9 F14 F14.0 F14.00 F14.01 F14.02 F14.03 F14.04 F14.05 F14.06
305F14.1 F14.2 F14.20 F14.200 F14.201 F14.202 F14.21 F14.22 F14.23 F14.24 F14.241
306F14.242 F14.25 F14.26 F14.3 F14.30 F14.31 F14.4 F14.40 F14.41 F14.5 F14.50
307F14.51 F14.52 F14.53 F14.54 F14.55 F14.56 F14.6 F14.7 F14.70 F14.71 F14.72
308F14.73 F14.74 F14.75 F14.8 F14.9 F15 F15.0 F15.00 F15.01 F15.02 F15.03 F15.04
309F15.05 F15.06 F15.1 F15.2 F15.20 F15.200 F15.201 F15.202 F15.21 F15.22 F15.23
310F15.24 F15.241 F15.242 F15.25 F15.26 F15.3 F15.30 F15.31 F15.4 F15.40 F15.41
311F15.5 F15.50 F15.51 F15.52 F15.53 F15.54 F15.55 F15.56 F15.6 F15.7 F15.70
312F15.71 F15.72 F15.73 F15.74 F15.75 F15.8 F15.9 F16 F16.0 F16.00 F16.01 F16.02
313F16.03 F16.04 F16.05 F16.06 F16.1 F16.2 F16.20 F16.200 F16.201 F16.202 F16.21
314F16.22 F16.23 F16.24 F16.241 F16.242 F16.25 F16.26 F16.3 F16.30 F16.31 F16.4
315F16.40 F16.41 F16.5 F16.50 F16.51 F16.52 F16.53 F16.54 F16.55 F16.56 F16.6
316F16.7 F16.70 F16.71 F16.72 F16.73 F16.74 F16.75 F16.8 F16.9 F17 F17.0 F17.00
317F17.01 F17.02 F17.03 F17.04 F17.05 F17.06 F17.1 F17.2 F17.20 F17.200 F17.201
318F17.202 F17.21 F17.22 F17.23 F17.24 F17.241 F17.242 F17.25 F17.26 F17.3 F17.30
319F17.31 F17.4 F17.40 F17.41 F17.5 F17.50 F17.51 F17.52 F17.53 F17.54 F17.55
320F17.56 F17.6 F17.7 F17.70 F17.71 F17.72 F17.73 F17.74 F17.75 F17.8 F17.9 F18
321F18.0 F18.00 F18.01 F18.02 F18.03 F18.04 F18.05 F18.06 F18.1 F18.2 F18.20
322F18.200 F18.201 F18.202 F18.21 F18.22 F18.23 F18.24 F18.241 F18.242 F18.25
323F18.26 F18.3 F18.30 F18.31 F18.4 F18.40 F18.41 F18.5 F18.50 F18.51 F18.52
324F18.53 F18.54 F18.55 F18.56 F18.6 F18.7 F18.70 F18.71 F18.72 F18.73 F18.74
325F18.75 F18.8 F18.9 F19 F19.0 F19.00 F19.01 F19.02 F19.03 F19.04 F19.05 F19.06
326F19.1 F19.2 F19.20 F19.200 F19.201 F19.202 F19.21 F19.22 F19.23 F19.24 F19.241
327F19.242 F19.25 F19.26 F19.3 F19.30 F19.31 F19.4 F19.40 F19.41 F19.5 F19.50
328F19.51 F19.52 F19.53 F19.54 F19.55 F19.56 F19.6 F19.7 F19.70 F19.71 F19.72
329F19.73 F19.74 F19.75 F19.8 F19.9 F20 F20.0 F20.1 F20.2 F20.3 F20.4 F20.5 F20.6
330F20.8 F20.9 F21 F22 F22.0 F22.8 F22.9 F23 F23.0 F23.1 F23.2 F23.3 F23.8 F23.9
331F23.90 F23.91 F24 F25 F25.0 F25.00 F25.01 F25.1 F25.10 F25.11 F25.2 F25.20
332F25.21 F25.8 F25.80 F25.81 F25.9 F25.90 F25.91 F28 F29 F30 F30.0 F30.1 F30.2
333F30.20 F30.21 F30.8 F30.9 F31 F31.0 F31.1 F31.2 F31.20 F31.21 F31.3 F31.30
334F31.31 F31.4 F31.5 F31.50 F31.51 F31.6 F31.7 F31.8 F31.9 F32 F32.0 F32.00
335F32.01 F32.1 F32.10 F32.11 F32.2 F32.3 F32.30 F32.31 F32.8 F32.9 F33 F33.0
336F33.00 F33.01 F33.1 F33.10 F33.11 F33.2 F33.3 F33.30 F33.31 F33.4 F33.8 F33.9
337F34 F34.0 F34.1 F34.8 F34.9 F38 F38.0 F38.00 F38.1 F38.10 F38.8 F39 F40 F40.0
338F40.00 F40.01 F40.1 F40.2 F40.8 F40.9 F41 F41.0 F41.00 F41.01 F41.1 F41.2 F41.3
339F41.8 F41.9 F42 F42.0 F42.1 F42.2 F42.8 F42.9 F43 F43.0 F43.00 F43.01 F43.02
340F43.1 F43.2 F43.20 F43.21 F43.22 F43.23 F43.24 F43.25 F43.28 F43.8 F43.9 F44
341F44.0 F44.1 F44.2 F44.3 F44.4 F44.5 F44.6 F44.7 F44.8 F44.80 F44.81 F44.82
342F44.88 F44.9 F45 F45.0 F45.1 F45.2 F45.3 F45.30 F45.31 F45.32 F45.33 F45.34
343F45.38 F45.4 F45.8 F45.9 F48 F48.0 F48.1 F48.8 F48.9 F50 F50.0 F50.1 F50.2
344F50.3 F50.4 F50.5 F50.8 F50.9 F51 F51.0 F51.1 F51.2 F51.3 F51.4 F51.5 F51.8
345F51.9 F52 F52.0 F52.1 F52.10 F52.11 F52.2 F52.3 F52.4 F52.5 F52.6 F52.7 F52.8
346F52.9 F53 F53.0 F53.1 F53.8 F53.9 F54 F55 F59 F60 F60.0 F60.1 F60.2 F60.3
347F60.30 F60.31 F60.4 F60.5 F60.6 F60.7 F60.8 F60.9 F61 F62 F62.0 F62.1 F62.8
348F62.9 F63 F63.0 F63.1 F63.2 F63.3 F63.8 F63.9 F64 F64.0 F64.1 F64.2 F64.8 F64.9
349F65 F65.0 F65.1 F65.2 F65.3 F65.4 F65.5 F65.6 F65.8 F65.9 F66 F66.0 F66.1 F66.2
350F66.8 F66.9 F66.90 F66.91 F66.92 F66.98 F68 F68.0 F68.1 F68.8 F69 F70 F70.0
351F70.1 F70.8 F70.9 F71 F71.0 F71.1 F71.8 F71.9 F72 F72.0 F72.1 F72.8 F72.9 F73
352F73.0 F73.1 F73.8 F73.9 F78 F78.0 F78.1 F78.8 F78.9 F79 F79.0 F79.1 F79.8 F79.9
353F80 F80.0 F80.1 F80.2 F80.3 F80.8 F80.9 F81 F81.0 F81.1 F81.2 F81.3 F81.8 F81.9
354F82 F83 F84 F84.0 F84.1 F84.10 F84.11 F84.12 F84.2 F84.3 F84.4 F84.5 F84.8
355F84.9 F88 F89 F90 F90.0 F90.1 F90.8 F90.9 F91 F91.0 F91.1 F91.2 F91.3 F91.8
356F91.9 F92 F92.0 F92.8 F92.9 F93 F93.0 F93.1 F93.2 F93.3 F93.8 F93.80 F93.9 F94
357F94.0 F94.1 F94.2 F94.8 F94.9 F95 F95.0 F95.1 F95.2 F95.8 F95.9 F98 F98.0
358F98.00 F98.01 F98.02 F98.1 F98.10 F98.11 F98.12 F98.2 F98.3 F98.4 F98.40 F98.41
359F98.42 F98.5 F98.6 F98.8 F98.9 F99 R40 R40.0 R40.1 R40.2 R41 R41.0 R41.1 R41.2
360R41.3 R41.8 R42 R43 R43.0 R43.1 R43.2 R43.8 R44 R44.0 R44.1 R44.2 R44.3 R44.8
361R45 R45.0 R45.1 R45.2 R45.3 R45.4 R45.5 R45.6 R45.7 R45.8 R46 R46.0 R46.1 R46.2
362R46.3 R46.4 R46.5 R46.6 R46.7 R46.8 X60 X60.0 X60.00 X60.01 X60.02 X60.03
363X60.04 X60.08 X60.09 X60.1 X60.10 X60.11 X60.12 X60.13 X60.14 X60.18 X60.19
364X60.2 X60.20 X60.21 X60.22 X60.23 X60.24 X60.28 X60.29 X60.3 X60.30 X60.31
365X60.32 X60.33 X60.34 X60.38 X60.39 X60.4 X60.40 X60.41 X60.42 X60.43 X60.44
366X60.48 X60.49 X60.5 X60.50 X60.51 X60.52 X60.53 X60.54 X60.58 X60.59 X60.6
367X60.60 X60.61 X60.62 X60.63 X60.64 X60.68 X60.69 X60.7 X60.70 X60.71 X60.72
368X60.73 X60.74 X60.78 X60.79 X60.8 X60.80 X60.81 X60.82 X60.83 X60.84 X60.88
369X60.89 X60.9 X60.90 X60.91 X60.92 X60.93 X60.94 X60.98 X60.99 X61 X61.0 X61.00
370X61.01 X61.02 X61.03 X61.04 X61.08 X61.09 X61.1 X61.10 X61.11 X61.12 X61.13
371X61.14 X61.18 X61.19 X61.2 X61.20 X61.21 X61.22 X61.23 X61.24 X61.28 X61.29
372X61.3 X61.30 X61.31 X61.32 X61.33 X61.34 X61.38 X61.39 X61.4 X61.40 X61.41
373X61.42 X61.43 X61.44 X61.48 X61.49 X61.5 X61.50 X61.51 X61.52 X61.53 X61.54
374X61.58 X61.59 X61.6 X61.60 X61.61 X61.62 X61.63 X61.64 X61.68 X61.69 X61.7
375X61.70 X61.71 X61.72 X61.73 X61.74 X61.78 X61.79 X61.8 X61.80 X61.81 X61.82
376X61.83 X61.84 X61.88 X61.89 X61.9 X61.90 X61.91 X61.92 X61.93 X61.94 X61.98
377X61.99 X62 X62.0 X62.00 X62.01 X62.02 X62.03 X62.04 X62.08 X62.09 X62.1 X62.10
378X62.11 X62.12 X62.13 X62.14 X62.18 X62.19 X62.2 X62.20 X62.21 X62.22 X62.23
379X62.24 X62.28 X62.29 X62.3 X62.30 X62.31 X62.32 X62.33 X62.34 X62.38 X62.39
380X62.4 X62.40 X62.41 X62.42 X62.43 X62.44 X62.48 X62.49 X62.5 X62.50 X62.51
381X62.52 X62.53 X62.54 X62.58 X62.59 X62.6 X62.60 X62.61 X62.62 X62.63 X62.64
382X62.68 X62.69 X62.7 X62.70 X62.71 X62.72 X62.73 X62.74 X62.78 X62.79 X62.8
383X62.80 X62.81 X62.82 X62.83 X62.84 X62.88 X62.89 X62.9 X62.90 X62.91 X62.92
384X62.93 X62.94 X62.98 X62.99 X63 X63.0 X63.00 X63.01 X63.02 X63.03 X63.04 X63.08
385X63.09 X63.1 X63.10 X63.11 X63.12 X63.13 X63.14 X63.18 X63.19 X63.2 X63.20
386X63.21 X63.22 X63.23 X63.24 X63.28 X63.29 X63.3 X63.30 X63.31 X63.32 X63.33
387X63.34 X63.38 X63.39 X63.4 X63.40 X63.41 X63.42 X63.43 X63.44 X63.48 X63.49
388X63.5 X63.50 X63.51 X63.52 X63.53 X63.54 X63.58 X63.59 X63.6 X63.60 X63.61
389X63.62 X63.63 X63.64 X63.68 X63.69 X63.7 X63.70 X63.71 X63.72 X63.73 X63.74
390X63.78 X63.79 X63.8 X63.80 X63.81 X63.82 X63.83 X63.84 X63.88 X63.89 X63.9
391X63.90 X63.91 X63.92 X63.93 X63.94 X63.98 X63.99 X64 X64.0 X64.00 X64.01 X64.02
392X64.03 X64.04 X64.08 X64.09 X64.1 X64.10 X64.11 X64.12 X64.13 X64.14 X64.18
393X64.19 X64.2 X64.20 X64.21 X64.22 X64.23 X64.24 X64.28 X64.29 X64.3 X64.30
394X64.31 X64.32 X64.33 X64.34 X64.38 X64.39 X64.4 X64.40 X64.41 X64.42 X64.43
395X64.44 X64.48 X64.49 X64.5 X64.50 X64.51 X64.52 X64.53 X64.54 X64.58 X64.59
396X64.6 X64.60 X64.61 X64.62 X64.63 X64.64 X64.68 X64.69 X64.7 X64.70 X64.71
397X64.72 X64.73 X64.74 X64.78 X64.79 X64.8 X64.80 X64.81 X64.82 X64.83 X64.84
398X64.88 X64.89 X64.9 X64.90 X64.91 X64.92 X64.93 X64.94 X64.98 X64.99 X65 X65.0
399X65.00 X65.01 X65.02 X65.03 X65.04 X65.08 X65.09 X65.1 X65.10 X65.11 X65.12
400X65.13 X65.14 X65.18 X65.19 X65.2 X65.20 X65.21 X65.22 X65.23 X65.24 X65.28
401X65.29 X65.3 X65.30 X65.31 X65.32 X65.33 X65.34 X65.38 X65.39 X65.4 X65.40
402X65.41 X65.42 X65.43 X65.44 X65.48 X65.49 X65.5 X65.50 X65.51 X65.52 X65.53
403X65.54 X65.58 X65.59 X65.6 X65.60 X65.61 X65.62 X65.63 X65.64 X65.68 X65.69
404X65.7 X65.70 X65.71 X65.72 X65.73 X65.74 X65.78 X65.79 X65.8 X65.80 X65.81
405X65.82 X65.83 X65.84 X65.88 X65.89 X65.9 X65.90 X65.91 X65.92 X65.93 X65.94
406X65.98 X65.99 X66 X66.0 X66.00 X66.01 X66.02 X66.03 X66.04 X66.08 X66.09 X66.1
407X66.10 X66.11 X66.12 X66.13 X66.14 X66.18 X66.19 X66.2 X66.20 X66.21 X66.22
408X66.23 X66.24 X66.28 X66.29 X66.3 X66.30 X66.31 X66.32 X66.33 X66.34 X66.38
409X66.39 X66.4 X66.40 X66.41 X66.42 X66.43 X66.44 X66.48 X66.49 X66.5 X66.50
410X66.51 X66.52 X66.53 X66.54 X66.58 X66.59 X66.6 X66.60 X66.61 X66.62 X66.63
411X66.64 X66.68 X66.69 X66.7 X66.70 X66.71 X66.72 X66.73 X66.74 X66.78 X66.79
412X66.8 X66.80 X66.81 X66.82 X66.83 X66.84 X66.88 X66.89 X66.9 X66.90 X66.91
413X66.92 X66.93 X66.94 X66.98 X66.99 X67 X67.0 X67.00 X67.01 X67.02 X67.03 X67.04
414X67.08 X67.09 X67.1 X67.10 X67.11 X67.12 X67.13 X67.14 X67.18 X67.19 X67.2
415X67.20 X67.21 X67.22 X67.23 X67.24 X67.28 X67.29 X67.3 X67.30 X67.31 X67.32
416X67.33 X67.34 X67.38 X67.39 X67.4 X67.40 X67.41 X67.42 X67.43 X67.44 X67.48
417X67.49 X67.5 X67.50 X67.51 X67.52 X67.53 X67.54 X67.58 X67.59 X67.6 X67.60
418X67.61 X67.62 X67.63 X67.64 X67.68 X67.69 X67.7 X67.70 X67.71 X67.72 X67.73
419X67.74 X67.78 X67.79 X67.8 X67.80 X67.81 X67.82 X67.83 X67.84 X67.88 X67.89
420X67.9 X67.90 X67.91 X67.92 X67.93 X67.94 X67.98 X67.99 X68 X68.0 X68.00 X68.01
421X68.02 X68.03 X68.04 X68.08 X68.09 X68.1 X68.10 X68.11 X68.12 X68.13 X68.14
422X68.18 X68.19 X68.2 X68.20 X68.21 X68.22 X68.23 X68.24 X68.28 X68.29 X68.3
423X68.30 X68.31 X68.32 X68.33 X68.34 X68.38 X68.39 X68.4 X68.40 X68.41 X68.42
424X68.43 X68.44 X68.48 X68.49 X68.5 X68.50 X68.51 X68.52 X68.53 X68.54 X68.58
425X68.59 X68.6 X68.60 X68.61 X68.62 X68.63 X68.64 X68.68 X68.69 X68.7 X68.70
426X68.71 X68.72 X68.73 X68.74 X68.78 X68.79 X68.8 X68.80 X68.81 X68.82 X68.83
427X68.84 X68.88 X68.89 X68.9 X68.90 X68.91 X68.92 X68.93 X68.94 X68.98 X68.99 X69
428X69.0 X69.00 X69.01 X69.02 X69.03 X69.04 X69.08 X69.09 X69.1 X69.10 X69.11
429X69.12 X69.13 X69.14 X69.18 X69.19 X69.2 X69.20 X69.21 X69.22 X69.23 X69.24
430X69.28 X69.29 X69.3 X69.30 X69.31 X69.32 X69.33 X69.34 X69.38 X69.39 X69.4
431X69.40 X69.41 X69.42 X69.43 X69.44 X69.48 X69.49 X69.5 X69.50 X69.51 X69.52
432X69.53 X69.54 X69.58 X69.59 X69.6 X69.60 X69.61 X69.62 X69.63 X69.64 X69.68
433X69.69 X69.7 X69.70 X69.71 X69.72 X69.73 X69.74 X69.78 X69.79 X69.8 X69.80
434X69.81 X69.82 X69.83 X69.84 X69.88 X69.89 X69.9 X69.90 X69.91 X69.92 X69.93
435X69.94 X69.98 X69.99 X70 X70.0 X70.00 X70.01 X70.02 X70.03 X70.04 X70.08 X70.09
436X70.1 X70.10 X70.11 X70.12 X70.13 X70.14 X70.18 X70.19 X70.2 X70.20 X70.21
437X70.22 X70.23 X70.24 X70.28 X70.29 X70.3 X70.30 X70.31 X70.32 X70.33 X70.34
438X70.38 X70.39 X70.4 X70.40 X70.41 X70.42 X70.43 X70.44 X70.48 X70.49 X70.5
439X70.50 X70.51 X70.52 X70.53 X70.54 X70.58 X70.59 X70.6 X70.60 X70.61 X70.62
440X70.63 X70.64 X70.68 X70.69 X70.7 X70.70 X70.71 X70.72 X70.73 X70.74 X70.78
441X70.79 X70.8 X70.80 X70.81 X70.82 X70.83 X70.84 X70.88 X70.89 X70.9 X70.90
442X70.91 X70.92 X70.93 X70.94 X70.98 X70.99 X71 X71.0 X71.00 X71.01 X71.02 X71.03
443X71.04 X71.08 X71.09 X71.1 X71.10 X71.11 X71.12 X71.13 X71.14 X71.18 X71.19
444X71.2 X71.20 X71.21 X71.22 X71.23 X71.24 X71.28 X71.29 X71.3 X71.30 X71.31
445X71.32 X71.33 X71.34 X71.38 X71.39 X71.4 X71.40 X71.41 X71.42 X71.43 X71.44
446X71.48 X71.49 X71.5 X71.50 X71.51 X71.52 X71.53 X71.54 X71.58 X71.59 X71.6
447X71.60 X71.61 X71.62 X71.63 X71.64 X71.68 X71.69 X71.7 X71.70 X71.71 X71.72
448X71.73 X71.74 X71.78 X71.79 X71.8 X71.80 X71.81 X71.82 X71.83 X71.84 X71.88
449X71.89 X71.9 X71.90 X71.91 X71.92 X71.93 X71.94 X71.98 X71.99 X72 X72.0 X72.00
450X72.01 X72.02 X72.03 X72.04 X72.08 X72.09 X72.1 X72.10 X72.11 X72.12 X72.13
451X72.14 X72.18 X72.19 X72.2 X72.20 X72.21 X72.22 X72.23 X72.24 X72.28 X72.29
452X72.3 X72.30 X72.31 X72.32 X72.33 X72.34 X72.38 X72.39 X72.4 X72.40 X72.41
453X72.42 X72.43 X72.44 X72.48 X72.49 X72.5 X72.50 X72.51 X72.52 X72.53 X72.54
454X72.58 X72.59 X72.6 X72.60 X72.61 X72.62 X72.63 X72.64 X72.68 X72.69 X72.7
455X72.70 X72.71 X72.72 X72.73 X72.74 X72.78 X72.79 X72.8 X72.80 X72.81 X72.82
456X72.83 X72.84 X72.88 X72.89 X72.9 X72.90 X72.91 X72.92 X72.93 X72.94 X72.98
457X72.99 X73 X73.0 X73.00 X73.01 X73.02 X73.03 X73.04 X73.08 X73.09 X73.1 X73.10
458X73.11 X73.12 X73.13 X73.14 X73.18 X73.19 X73.2 X73.20 X73.21 X73.22 X73.23
459X73.24 X73.28 X73.29 X73.3 X73.30 X73.31 X73.32 X73.33 X73.34 X73.38 X73.39
460X73.4 X73.40 X73.41 X73.42 X73.43 X73.44 X73.48 X73.49 X73.5 X73.50 X73.51
461X73.52 X73.53 X73.54 X73.58 X73.59 X73.6 X73.60 X73.61 X73.62 X73.63 X73.64
462X73.68 X73.69 X73.7 X73.70 X73.71 X73.72 X73.73 X73.74 X73.78 X73.79 X73.8
463X73.80 X73.81 X73.82 X73.83 X73.84 X73.88 X73.89 X73.9 X73.90 X73.91 X73.92
464X73.93 X73.94 X73.98 X73.99 X74 X74.0 X74.00 X74.01 X74.02 X74.03 X74.04 X74.08
465X74.09 X74.1 X74.10 X74.11 X74.12 X74.13 X74.14 X74.18 X74.19 X74.2 X74.20
466X74.21 X74.22 X74.23 X74.24 X74.28 X74.29 X74.3 X74.30 X74.31 X74.32 X74.33
467X74.34 X74.38 X74.39 X74.4 X74.40 X74.41 X74.42 X74.43 X74.44 X74.48 X74.49
468X74.5 X74.50 X74.51 X74.52 X74.53 X74.54 X74.58 X74.59 X74.6 X74.60 X74.61
469X74.62 X74.63 X74.64 X74.68 X74.69 X74.7 X74.70 X74.71 X74.72 X74.73 X74.74
470X74.78 X74.79 X74.8 X74.80 X74.81 X74.82 X74.83 X74.84 X74.88 X74.89 X74.9
471X74.90 X74.91 X74.92 X74.93 X74.94 X74.98 X74.99 X75 X75.0 X75.00 X75.01 X75.02
472X75.03 X75.04 X75.08 X75.09 X75.1 X75.10 X75.11 X75.12 X75.13 X75.14 X75.18
473X75.19 X75.2 X75.20 X75.21 X75.22 X75.23 X75.24 X75.28 X75.29 X75.3 X75.30
474X75.31 X75.32 X75.33 X75.34 X75.38 X75.39 X75.4 X75.40 X75.41 X75.42 X75.43
475X75.44 X75.48 X75.49 X75.5 X75.50 X75.51 X75.52 X75.53 X75.54 X75.58 X75.59
476X75.6 X75.60 X75.61 X75.62 X75.63 X75.64 X75.68 X75.69 X75.7 X75.70 X75.71
477X75.72 X75.73 X75.74 X75.78 X75.79 X75.8 X75.80 X75.81 X75.82 X75.83 X75.84
478X75.88 X75.89 X75.9 X75.90 X75.91 X75.92 X75.93 X75.94 X75.98 X75.99 X76 X76.0
479X76.00 X76.01 X76.02 X76.03 X76.04 X76.08 X76.09 X76.1 X76.10 X76.11 X76.12
480X76.13 X76.14 X76.18 X76.19 X76.2 X76.20 X76.21 X76.22 X76.23 X76.24 X76.28
481X76.29 X76.3 X76.30 X76.31 X76.32 X76.33 X76.34 X76.38 X76.39 X76.4 X76.40
482X76.41 X76.42 X76.43 X76.44 X76.48 X76.49 X76.5 X76.50 X76.51 X76.52 X76.53
483X76.54 X76.58 X76.59 X76.6 X76.60 X76.61 X76.62 X76.63 X76.64 X76.68 X76.69
484X76.7 X76.70 X76.71 X76.72 X76.73 X76.74 X76.78 X76.79 X76.8 X76.80 X76.81
485X76.82 X76.83 X76.84 X76.88 X76.89 X76.9 X76.90 X76.91 X76.92 X76.93 X76.94
486X76.98 X76.99 X77 X77.0 X77.00 X77.01 X77.02 X77.03 X77.04 X77.08 X77.09 X77.1
487X77.10 X77.11 X77.12 X77.13 X77.14 X77.18 X77.19 X77.2 X77.20 X77.21 X77.22
488X77.23 X77.24 X77.28 X77.29 X77.3 X77.30 X77.31 X77.32 X77.33 X77.34 X77.38
489X77.39 X77.4 X77.40 X77.41 X77.42 X77.43 X77.44 X77.48 X77.49 X77.5 X77.50
490X77.51 X77.52 X77.53 X77.54 X77.58 X77.59 X77.6 X77.60 X77.61 X77.62 X77.63
491X77.64 X77.68 X77.69 X77.7 X77.70 X77.71 X77.72 X77.73 X77.74 X77.78 X77.79
492X77.8 X77.80 X77.81 X77.82 X77.83 X77.84 X77.88 X77.89 X77.9 X77.90 X77.91
493X77.92 X77.93 X77.94 X77.98 X77.99 X78 X78.0 X78.00 X78.01 X78.02 X78.03 X78.04
494X78.08 X78.09 X78.1 X78.10 X78.11 X78.12 X78.13 X78.14 X78.18 X78.19 X78.2
495X78.20 X78.21 X78.22 X78.23 X78.24 X78.28 X78.29 X78.3 X78.30 X78.31 X78.32
496X78.33 X78.34 X78.38 X78.39 X78.4 X78.40 X78.41 X78.42 X78.43 X78.44 X78.48
497X78.49 X78.5 X78.50 X78.51 X78.52 X78.53 X78.54 X78.58 X78.59 X78.6 X78.60
498X78.61 X78.62 X78.63 X78.64 X78.68 X78.69 X78.7 X78.70 X78.71 X78.72 X78.73
499X78.74 X78.78 X78.79 X78.8 X78.80 X78.81 X78.82 X78.83 X78.84 X78.88 X78.89
500X78.9 X78.90 X78.91 X78.92 X78.93 X78.94 X78.98 X78.99 X79 X79.0 X79.00 X79.01
501X79.02 X79.03 X79.04 X79.08 X79.09 X79.1 X79.10 X79.11 X79.12 X79.13 X79.14
502X79.18 X79.19 X79.2 X79.20 X79.21 X79.22 X79.23 X79.24 X79.28 X79.29 X79.3
503X79.30 X79.31 X79.32 X79.33 X79.34 X79.38 X79.39 X79.4 X79.40 X79.41 X79.42
504X79.43 X79.44 X79.48 X79.49 X79.5 X79.50 X79.51 X79.52 X79.53 X79.54 X79.58
505X79.59 X79.6 X79.60 X79.61 X79.62 X79.63 X79.64 X79.68 X79.69 X79.7 X79.70
506X79.71 X79.72 X79.73 X79.74 X79.78 X79.79 X79.8 X79.80 X79.81 X79.82 X79.83
507X79.84 X79.88 X79.89 X79.9 X79.90 X79.91 X79.92 X79.93 X79.94 X79.98 X79.99 X80
508X80.0 X80.00 X80.01 X80.02 X80.03 X80.04 X80.08 X80.09 X80.1 X80.10 X80.11
509X80.12 X80.13 X80.14 X80.18 X80.19 X80.2 X80.20 X80.21 X80.22 X80.23 X80.24
510X80.28 X80.29 X80.3 X80.30 X80.31 X80.32 X80.33 X80.34 X80.38 X80.39 X80.4
511X80.40 X80.41 X80.42 X80.43 X80.44 X80.48 X80.49 X80.5 X80.50 X80.51 X80.52
512X80.53 X80.54 X80.58 X80.59 X80.6 X80.60 X80.61 X80.62 X80.63 X80.64 X80.68
513X80.69 X80.7 X80.70 X80.71 X80.72 X80.73 X80.74 X80.78 X80.79 X80.8 X80.80
514X80.81 X80.82 X80.83 X80.84 X80.88 X80.89 X80.9 X80.90 X80.91 X80.92 X80.93
515X80.94 X80.98 X80.99 X81 X81.0 X81.00 X81.01 X81.02 X81.03 X81.04 X81.08 X81.09
516X81.1 X81.10 X81.11 X81.12 X81.13 X81.14 X81.18 X81.19 X81.2 X81.20 X81.21
517X81.22 X81.23 X81.24 X81.28 X81.29 X81.3 X81.30 X81.31 X81.32 X81.33 X81.34
518X81.38 X81.39 X81.4 X81.40 X81.41 X81.42 X81.43 X81.44 X81.48 X81.49 X81.5
519X81.50 X81.51 X81.52 X81.53 X81.54 X81.58 X81.59 X81.6 X81.60 X81.61 X81.62
520X81.63 X81.64 X81.68 X81.69 X81.7 X81.70 X81.71 X81.72 X81.73 X81.74 X81.78
521X81.79 X81.8 X81.80 X81.81 X81.82 X81.83 X81.84 X81.88 X81.89 X81.9 X81.90
522X81.91 X81.92 X81.93 X81.94 X81.98 X81.99 X82 X82.0 X82.00 X82.01 X82.02 X82.03
523X82.04 X82.08 X82.09 X82.1 X82.10 X82.11 X82.12 X82.13 X82.14 X82.18 X82.19
524X82.2 X82.20 X82.21 X82.22 X82.23 X82.24 X82.28 X82.29 X82.3 X82.30 X82.31
525X82.32 X82.33 X82.34 X82.38 X82.39 X82.4 X82.40 X82.41 X82.42 X82.43 X82.44
526X82.48 X82.49 X82.5 X82.50 X82.51 X82.52 X82.53 X82.54 X82.58 X82.59 X82.6
527X82.60 X82.61 X82.62 X82.63 X82.64 X82.68 X82.69 X82.7 X82.70 X82.71 X82.72
528X82.73 X82.74 X82.78 X82.79 X82.8 X82.80 X82.81 X82.82 X82.83 X82.84 X82.88
529X82.89 X82.9 X82.90 X82.91 X82.92 X82.93 X82.94 X82.98 X82.99 X83 X83.0 X83.00
530X83.01 X83.02 X83.03 X83.04 X83.08 X83.09 X83.1 X83.10 X83.11 X83.12 X83.13
531X83.14 X83.18 X83.19 X83.2 X83.20 X83.21 X83.22 X83.23 X83.24 X83.28 X83.29
532X83.3 X83.30 X83.31 X83.32 X83.33 X83.34 X83.38 X83.39 X83.4 X83.40 X83.41
533X83.42 X83.43 X83.44 X83.48 X83.49 X83.5 X83.50 X83.51 X83.52 X83.53 X83.54
534X83.58 X83.59 X83.6 X83.60 X83.61 X83.62 X83.63 X83.64 X83.68 X83.69 X83.7
535X83.70 X83.71 X83.72 X83.73 X83.74 X83.78 X83.79 X83.8 X83.80 X83.81 X83.82
536X83.83 X83.84 X83.88 X83.89 X83.9 X83.90 X83.91 X83.92 X83.93 X83.94 X83.98
537X83.99 X84 X84.0 X84.00 X84.01 X84.02 X84.03 X84.04 X84.08 X84.09 X84.1 X84.10
538X84.11 X84.12 X84.13 X84.14 X84.18 X84.19 X84.2 X84.20 X84.21 X84.22 X84.23
539X84.24 X84.28 X84.29 X84.3 X84.30 X84.31 X84.32 X84.33 X84.34 X84.38 X84.39
540X84.4 X84.40 X84.41 X84.42 X84.43 X84.44 X84.48 X84.49 X84.5 X84.50 X84.51
541X84.52 X84.53 X84.54 X84.58 X84.59 X84.6 X84.60 X84.61 X84.62 X84.63 X84.64
542X84.68 X84.69 X84.7 X84.70 X84.71 X84.72 X84.73 X84.74 X84.78 X84.79 X84.8
543X84.80 X84.81 X84.82 X84.83 X84.84 X84.88 X84.89 X84.9 X84.90 X84.91 X84.92
544X84.93 X84.94 X84.98 X84.99 Z00.4 Z03.2 Z71.1
545""".split()
546)
549# =============================================================================
550# The SnomedConcept class, amended
551# =============================================================================
554class SnomedConcept(SnomedConceptCardinalPythonlib):
555 @classmethod
556 def create(
557 cls, concept: SnomedConceptCardinalPythonlib
558 ) -> "SnomedConcept":
559 """
560 Creates a CamCOPS-friendly
561 :class:`camcops_server.cc_modules.cc_snomed.SnomedConcept` from a
562 :class:`cardinal_pythonlib.snomed.SnomedConcept`.
564 The result has extra methods.
565 """
566 return SnomedConcept(identifier=concept.identifier, term=concept.term)
568 def xml_element(self, longform: bool = True) -> XmlElement:
569 """
570 Returns a :class:`camcops_server.cc_modules.cc_xml.XmlElement` for this
571 SNOMED-CT object.
573 Args:
574 longform: print SNOMED-CT concepts in long form?
575 """
576 return XmlElement(
577 name=SNOMED_XML_NAME,
578 value=self.as_string(longform),
579 datatype=XmlDataTypes.STRING,
580 )
583# =============================================================================
584# The SnomedExpression class, amended
585# =============================================================================
588class SnomedExpression(SnomedExpressionCardinalPythonlib):
589 def xml_element(self, longform: bool = True) -> XmlElement:
590 """
591 Returns a :class:`camcops_server.cc_modules.cc_xml.XmlElement` for this
592 SNOMED-CT object.
594 Args:
595 longform: print SNOMED-CT expressions in long form?
596 """
597 return XmlElement(
598 name=SNOMED_XML_NAME,
599 value=self.as_string(longform),
600 datatype=XmlDataTypes.STRING,
601 )
604# =============================================================================
605# The CamCOPS XML file format for SNOMED-CT
606# =============================================================================
608ROOT_TAG = "snomed_concepts"
609CONCEPT_TAG = "concept"
610LOOKUP_TAG = "lookup"
611LOOKUP_NAME_ATTR = "name"
612LOOKUP_ATTR = "lookup"
613ID_TAG = "id"
614TERM_TAG = "term"
615AUTOGEN_COMMENT = (
616 "Autogenerated XML (see camcops_server.cc_modules.cc_snomed.py); do not "
617 "edit"
618)
621def get_snomed_concepts_from_xml(
622 xml_filename: str,
623) -> Dict[str, Union[SnomedConcept, List[SnomedConcept]]]:
624 """
625 Reads in all SNOMED-CT concepts from an XML file according to the CamCOPS
626 format.
628 Args:
629 xml_filename: XML filename to read
631 Returns:
632 dict: mapping each lookup code found to a list of
633 :class:`SnomedConcept` objects
635 """
636 log.info("Reading SNOMED-CT XML file: {}", xml_filename)
637 parser = ElementTree.XMLParser(encoding="UTF-8")
638 tree = ElementTree.parse(xml_filename, parser=parser)
639 root = tree.getroot()
640 all_concepts = {} # type: Dict[str, List[SnomedConcept]]
641 find_lookup = "./{tag}[@{attr}]".format(
642 tag=LOOKUP_TAG, attr=LOOKUP_NAME_ATTR
643 )
644 find_concept = "./{tag}".format(tag=CONCEPT_TAG)
645 find_id_in_concept = "./{tag}".format(tag=ID_TAG)
646 find_name_in_concept = "./{tag}".format(tag=TERM_TAG)
647 for lookuproot in root.findall(find_lookup):
648 # Extract info from the XML
649 lookupname = lookuproot.attrib.get(LOOKUP_NAME_ATTR)
650 for conceptroot in lookuproot.findall(find_concept):
651 id_node = conceptroot.find(find_id_in_concept)
652 identifier = int(id_node.text)
653 name_node = conceptroot.find(find_name_in_concept)
654 name = name_node.text or ""
655 # Stash it
656 concept = SnomedConcept(identifier, name)
657 concepts_for_lookup = all_concepts.setdefault(lookupname, [])
658 concepts_for_lookup.append(concept)
659 # Done
660 return all_concepts # type: ignore[return-value]
663def write_snomed_concepts_to_xml(
664 xml_filename: str,
665 concepts: Dict[str, List[SnomedConcept]],
666 comment: str = AUTOGEN_COMMENT,
667) -> None:
668 """
669 Writes SNOMED-CT concepts to an XML file in the CamCOPS format.
671 Args:
672 xml_filename: XML filename to write
673 concepts: dictionary mapping lookup codes to a list of
674 :class:`SnomedConcept` objects
675 comment: comment for XML file
676 """
677 # https://stackoverflow.com/questions/3605680/creating-a-simple-xml-file-using-python
678 root = ElementTree.Element(ROOT_TAG)
679 comment_element = ElementTree.Comment(comment)
680 root.insert(0, comment_element)
681 for lookup, concepts_for_lookup in concepts.items():
682 l_el = ElementTree.SubElement(
683 root, LOOKUP_TAG, {LOOKUP_NAME_ATTR: lookup}
684 )
685 for concept in concepts_for_lookup:
686 c_el = ElementTree.SubElement(l_el, CONCEPT_TAG)
687 i_el = ElementTree.SubElement(c_el, ID_TAG)
688 i_el.text = str(concept.identifier)
689 n_el = ElementTree.SubElement(c_el, TERM_TAG)
690 n_el.text = concept.term
691 tree = ElementTree.ElementTree(root)
692 log.info("Writing to {!r}", xml_filename)
693 tree.write(xml_filename)
696# =============================================================================
697# SNOMED-CT concepts for CamCOPS tasks
698# =============================================================================
700# -----------------------------------------------------------------------------
701# CamCOPS lookup codes for SNOMED-CT concepts
702# -----------------------------------------------------------------------------
705class SnomedLookup(object):
706 """
707 We're not allowed to embed SNOMED-CT codes in the CamCOPS code. Therefore,
708 within CamCOPS, we use string constants represented in this class. If the
709 local institution is allowed (e.g. in the UK, as below), then it can
710 install additional data.
712 - UK license:
713 https://isd.digital.nhs.uk/trud3/user/guest/group/0/pack/26/subpack/101/licences
715 - To find codes: https://termbrowser.nhs.uk/
717 Abbreviations:
719 - "Finding" is not abbreviated
720 - "Obs" or "observable" is short for "observable entity"
721 - "Procedure" is not abbreviated
722 - "Scale" is short for "assessment scale"
723 - "Situation" is not abbreviated
725 Variable names are designed for clear code. Value strings are designed for
726 clear XML that matches SNOMED-CT, in the format TASK_CONCEPTTYPE_NAME.
728 """
730 # https://snomedbrowser.com/Codes/Details/XXX
732 # -------------------------------------------------------------------------
733 # SNOMED-CT core concepts
734 # -------------------------------------------------------------------------
736 # Base concepts
737 OBSERVABLE_ENTITY = "observable_entity"
739 # Abstract physical quantities
740 MASS = "mass"
741 LENGTH = "length"
743 # Saying "units"
744 UNIT_OF_MEASURE = "unit_of_measure"
746 # Base physical units
747 KILOGRAM = "kilogram"
748 METRE = "metre"
749 CENTIMETRE = "centimetre"
751 # Compound physical units
752 KG_PER_SQ_M = "kilogram_per_square_metre"
754 # -------------------------------------------------------------------------
755 # Scales
756 # -------------------------------------------------------------------------
758 # ACE-R
759 ACE_R_SCALE = "ace_r_scale"
760 ACE_R_SUBSCALE_ATTENTION_ORIENTATION = (
761 "ace_r_subscale_attention_orientation"
762 )
763 ACE_R_SUBSCALE_FLUENCY = "ace_r_subscale_fluency"
764 ACE_R_SUBSCALE_LANGUAGE = "ace_r_subscale_language"
765 ACE_R_SUBSCALE_MEMORY = "ace_r_subscale_memory"
766 ACE_R_SUBSCALE_VISUOSPATIAL = "ace_r_subscale_visuospatial"
767 ACE_R_SCORE = "ace_r_observable_score"
768 ACE_R_SUBSCORE_ATTENTION_ORIENTATION = (
769 "ace_r_observable_subscore_attention_orientation"
770 )
771 ACE_R_SUBSCORE_FLUENCY = "ace_r_observable_subscore_fluency"
772 ACE_R_SUBSCORE_LANGUAGE = "ace_r_observable_subscore_language"
773 ACE_R_SUBSCORE_MEMORY = "ace_r_observable_subscore_memory"
774 ACE_R_SUBSCORE_VISUOSPATIAL = "ace_r_observable_subscore_visuospatial"
775 ACE_R_PROCEDURE_ASSESSMENT = "ace_r_procedure_assessment"
776 ACE_R_PROCEDURE_ASSESSMENT_SUBSCALE_ATTENTION_ORIENTATION = (
777 "ace_r_procedure_assessment_subscale_attention_orientation"
778 )
779 ACE_R_PROCEDURE_ASSESSMENT_SUBSCALE_FLUENCY = (
780 "ace_r_procedure_assessment_subscale_fluency"
781 )
782 ACE_R_PROCEDURE_ASSESSMENT_SUBSCALE_LANGUAGE = (
783 "ace_r_procedure_assessment_subscale_language"
784 )
785 ACE_R_PROCEDURE_ASSESSMENT_SUBSCALE_MEMORY = (
786 "ace_r_procedure_assessment_subscale_memory"
787 )
788 ACE_R_PROCEDURE_ASSESSMENT_SUBSCALE_VISUOSPATIAL = (
789 "ace_r_procedure_assessment_subscale_visuospatial"
790 )
792 # AIMS
793 AIMS_SCALE = "aims_scale"
794 AIMS_TOTAL_SCORE = "aims_observable_total_score"
795 AIMS_PROCEDURE_ASSESSMENT = "aims_procedure_assessment"
797 # AUDIT, AUDIT-C
798 AUDIT_SCALE = "audit_scale"
799 AUDIT_SCORE = "audit_observable_score"
800 AUDIT_PROCEDURE_ASSESSMENT = "audit_procedure_assessment"
801 AUDITC_SCALE = "auditc_scale"
802 AUDITC_SCORE = "auditc_observable_score"
803 AUDITC_PROCEDURE_ASSESSMENT = "auditc_procedure_assessment"
805 # BADLS
806 BADLS_SCALE = "badls_scale"
807 BADLS_SCORE = "badls_observable_score"
808 BADLS_PROCEDURE_ASSESSMENT = "badls_procedure_assessment"
810 # BDI
811 BDI_SCALE = "bdi_scale"
812 BDI_SCORE = "bdi_observable_score"
813 BDI_PROCEDURE_ASSESSMENT = "bdi_procedure_assessment"
814 BDI_II_SCORE = "bdi_ii_observable_score"
815 BDI_II_PROCEDURE_ASSESSMENT = "bdi_ii_procedure_assessment"
817 # BMI
818 BMI_OBSERVABLE = "bmi_observable"
819 BMI_PROCEDURE_MEASUREMENT = "bmi_procedure_measurement"
820 BODY_HEIGHT_OBSERVABLE = "body_height_observable"
821 BODY_WEIGHT_OBSERVABLE = "body_weight_observable"
822 WAIST_CIRCUMFERENCE_PROCEDURE_MEASUREMENT = (
823 "waist_circumference_procedure_measurement"
824 )
825 WAIST_CIRCUMFERENCE_OBSERVABLE = "waist_circumference_observable"
827 # BPRS, BPRS-E
828 BPRS1962_SCALE = "bprs1962_scale"
829 # no observable/procedure
831 # CAGE
832 CAGE_SCALE = "cage_scale"
833 CAGE_SCORE = "cage_observable_score"
834 CAGE_PROCEDURE_ASSESSMENT = "cage_procedure_assessment"
836 # CAPE-42: none
837 # CAPS: none
838 # Cardinal RN, Expectation-Detection: none
839 # CBI-R: none
840 # CECA-Q3: none
841 # CESD, CESD-R: none
842 # CGI, CGI-I, CGI-SCH: none
843 # CIS-R: none
845 # CIWA-Ar
846 CIWA_AR_SCALE = "ciwa_ar_scale"
847 CIWA_AR_SCORE = "ciwa_ar_observable_score"
848 CIWA_AR_PROCEDURE_ASSESSMENT = "ciwa_ar_procedure_assessment"
850 # Clinical: progress note
851 PROGRESS_NOTE_PROCEDURE = "progress_note_procedure"
852 CLINICAL_NOTE = "clinical_note"
854 # Clinical: photograph
855 PHOTOGRAPH_PROCEDURE = "photograph_procedure"
856 PHOTOGRAPH_PHYSICAL_OBJECT = "photograph_physical_object"
858 # Clinical: psychiatric clerking
859 # ... "location": not obvious
860 # ... "contact type" is an AoMRC heading, but I'm not sure the observable
861 # entity of "Initial contact type" is right.
862 #
863 # Deprecated between v20191001 and v20210929:
864 # PSYCHIATRIC_ASSESSMENT_PROCEDURE = "psychiatric_assessment_procedure"
865 DIAGNOSTIC_PSYCHIATRIC_INTERVIEW_PROCEDURE = (
866 "diagnostic_psychiatric_interview_procedure"
867 )
869 PSYCLERK_REASON_FOR_REFERRAL = "psyclerk_reason_for_referral"
870 PSYCLERK_PRESENTING_ISSUE = "psyclerk_presenting_issue"
871 PSYCLERK_SYSTEMS_REVIEW = "psyclerk_systems_review"
872 PSYCLERK_COLLATERAL_HISTORY = "psyclerk_collateral_history"
874 PSYCLERK_PAST_MEDICAL_SURGICAL_MENTAL_HEALTH_HISTORY = (
875 "psyclerk_past_medical_surgical_mental_health_history"
876 )
877 PSYCLERK_PROCEDURES = "psyclerk_procedures"
878 PSYCLERK_ALLERGIES_ADVERSE_REACTIONS = (
879 "psyclerk_allergies_adverse_reactions"
880 )
881 PSYCLERK_MEDICATIONS_MEDICAL_DEVICES = (
882 "psyclerk_medications_medical_devices"
883 )
884 PSYCLERK_DRUG_SUBSTANCE_USE = "psyclerk_drug_substance_use"
885 PSYCLERK_FAMILY_HISTORY = "psyclerk_family_history"
886 PSYCLERK_DEVELOPMENTAL_HISTORY = "psyclerk_developmental_history"
887 PSYCLERK_SOCIAL_PERSONAL_HISTORY = "psyclerk_social_personal_history"
888 PSYCLERK_PERSONALITY = "psyclerk_personality"
889 PSYCLERK_PRISON_RECORD_CRIMINAL_ACTIVITY = (
890 "psyclerk_prison_record_criminal_activity"
891 )
892 PSYCLERK_SOCIAL_HISTORY_BASELINE = "psyclerk_social_history_baseline"
894 PSYCLERK_MSE_APPEARANCE = "psyclerk_mse_appearance"
895 PSYCLERK_MSE_BEHAVIOUR = "psyclerk_mse_behaviour"
896 PSYCLERK_MSE_SPEECH = "psyclerk_mse_speech"
897 PSYCLERK_MSE_MOOD = "psyclerk_mse_mood"
898 PSYCLERK_MSE_AFFECT = "psyclerk_mse_affect"
899 PSYCLERK_MSE_THOUGHT = "psyclerk_mse_thought"
900 PSYCLERK_MSE_PERCEPTION = "psyclerk_mse_perception"
901 PSYCLERK_MSE_COGNITION = "psyclerk_mse_cognition"
902 PSYCLERK_MSE_INSIGHT = "psyclerk_mse_insight"
904 PSYCLERK_PHYSEXAM_GENERAL = "psyclerk_physexam_general"
905 PSYCLERK_PHYSEXAM_CARDIOVASCULAR = "psyclerk_physexam_cardiovascular"
906 PSYCLERK_PHYSEXAM_RESPIRATORY = "psyclerk_physexam_respiratory"
907 PSYCLERK_PHYSEXAM_ABDOMINAL = "psyclerk_physexam_abdominal"
908 PSYCLERK_PHYSEXAM_NEUROLOGICAL = "psyclerk_physexam_neurological"
910 PSYCLERK_ASSESSMENT_SCALES = "psyclerk_assessment_scales"
911 PSYCLERK_INVESTIGATIONS_RESULTS = "psyclerk_investigations_results"
913 PSYCLERK_SAFETY_ALERTS = "psyclerk_safety_alerts"
914 PSYCLERK_RISK_ASSESSMENT = "psyclerk_risk_assessment"
915 PSYCLERK_RELEVANT_LEGAL_INFORMATION = "psyclerk_relevant_legal_information"
917 PSYCLERK_CURRENT_PROBLEMS = "psyclerk_current_problems"
918 PSYCLERK_PATIENT_CARER_CONCERNS = "psyclerk_patient_carer_concerns"
919 PSYCLERK_CLINICAL_NARRATIVE = "psyclerk_clinical_narrative"
920 PSYCLERK_MANAGEMENT_PLAN = "psyclerk_management_plan"
921 PSYCLERK_INFORMATION_GIVEN = "psyclerk_information_given"
923 # CPFT/CUH LPS: none
924 # COPE: none
926 # CORE-10
927 CORE10_SCALE = "core10_scale"
928 CORE10_SCORE = "core10_observable_score"
929 CORE10_PROCEDURE_ASSESSMENT = "core10_procedure_assessment"
931 # DAD: none
933 # DAST
934 DAST_SCALE = "dast_scale"
935 # I think the similarly named codes represent urine screening.
937 # Deakin JB, antibody: none
938 # Demo questionnaire: none
939 # DEMQOL, DEMQOL-Proxy: none
940 # Distress Thermometer: none
942 # EQ-5D-5L
943 EQ5D5L_SCALE = "eq5d5l_scale"
944 EQ5D5L_INDEX_VALUE = "eq5d5l_observable_index_value"
945 EQ5D5L_PAIN_DISCOMFORT_SCORE = "eq5d5l_observable_pain_discomfort_score"
946 EQ5D5L_USUAL_ACTIVITIES_SCORE = "eq5d5l_observable_usual_activities_score"
947 EQ5D5L_ANXIETY_DEPRESSION_SCORE = (
948 "eq5d5l_observable_anxiety_depression_score"
949 )
950 EQ5D5L_MOBILITY_SCORE = "eq5d5l_observable_mobility_score"
951 EQ5D5L_SELF_CARE_SCORE = "eq5d5l_observable_self_care_score"
952 EQ5D5L_PROCEDURE_ASSESSMENT = "eq5d5l_procedure_assessment"
954 # FACT-G: none
956 # FAST: none
957 FAST_SCALE = "fast_scale"
958 FAST_SCORE = "fast_observable_score"
959 FAST_PROCEDURE_ASSESSMENT = "fast_procedure_assessment"
961 # IRAC: none
962 # FFT: none
964 # Patient Satisfaction Scale
965 # Not sure. See XML
967 # Referrer Satisfaction Scale (patient-specific, survey): none
968 # Frontotemporal Dementia Rating Scale: none
970 # GAD-7
971 GAD7_SCALE = "gad7_scale"
972 GAD7_SCORE = "gad7_observable_score"
973 GAD7_PROCEDURE_ASSESSMENT = "gad7_procedure_assessment"
975 # GAF
976 GAF_SCALE = "gaf_scale"
977 # no observable/procedure
979 # GDS-15
980 GDS15_SCALE = "gds15_scale"
981 GDS15_SCORE = "gds15_observable_score"
982 GDS15_PROCEDURE_ASSESSMENT = "gds15_procedure_assessment"
984 # UK GMC Patient Questionnaire: none
986 # HADS, HADS-respondent
987 HADS_SCALE = "hads_scale"
988 HADS_ANXIETY_SCORE = "hads_observable_anxiety_score"
989 HADS_DEPRESSION_SCORE = "hads_observable_depression_score"
990 HADS_PROCEDURE_ASSESSMENT = "hads_procedure_assessment"
992 # HAMA: none
994 # HAMD
995 HAMD_SCALE = "hamd_scale"
996 HAMD_SCORE = "hamd_observable_score"
997 HAMD_PROCEDURE_ASSESSMENT = "hamd_procedure_assessment"
999 # HAMD-7: none
1001 # HoNOS, HoNOS-65+, HoNOSCA, etc. (there are others too)
1002 HONOSCA_SCALE = "honos_childrenadolescents_scale"
1003 HONOSCA_SECTION_A_SCALE = "honos_childrenadolescents_section_a_scale"
1004 HONOSCA_SECTION_B_SCALE = "honos_childrenadolescents_section_b_scale"
1005 HONOSCA_SCORE = "honos_childrenadolescents_observable_score"
1006 HONOSCA_SECTION_A_SCORE = (
1007 "honos_childrenadolescents_observable_section_a_score"
1008 )
1009 HONOSCA_SECTION_B_SCORE = (
1010 "honos_childrenadolescents_observable_section_b_score"
1011 )
1012 HONOSCA_SECTION_A_PLUS_B_SCORE = (
1013 "honos_childrenadolescents_observable_section_a_plus_b_score"
1014 )
1015 HONOSCA_PROCEDURE_ASSESSMENT = (
1016 "honos_childrenadolescents_procedure_assessment"
1017 )
1018 #
1019 HONOS65_SCALE = "honos_olderadults_scale"
1020 HONOS65_SCORE = "honos_olderadults_observable_score"
1021 HONOS65_PROCEDURE_ASSESSMENT = "honos_olderadults_procedure_assessment"
1022 #
1023 HONOSWA_SCALE = "honos_workingage_scale"
1024 HONOSWA_SUBSCALE_1_OVERACTIVE = "honos_workingage_subscale_1_overactive"
1025 HONOSWA_SUBSCALE_2_SELFINJURY = "honos_workingage_subscale_2_selfinjury"
1026 HONOSWA_SUBSCALE_3_SUBSTANCE = "honos_workingage_subscale_3_substance"
1027 HONOSWA_SUBSCALE_4_COGNITIVE = "honos_workingage_subscale_4_cognitive"
1028 HONOSWA_SUBSCALE_5_PHYSICAL = "honos_workingage_subscale_5_physical"
1029 HONOSWA_SUBSCALE_6_PSYCHOSIS = "honos_workingage_subscale_6_psychosis"
1030 HONOSWA_SUBSCALE_7_DEPRESSION = "honos_workingage_subscale_7_depression"
1031 HONOSWA_SUBSCALE_8_OTHERMENTAL = "honos_workingage_subscale_8_othermental"
1032 HONOSWA_SUBSCALE_9_RELATIONSHIPS = (
1033 "honos_workingage_subscale_9_relationships"
1034 )
1035 HONOSWA_SUBSCALE_10_ADL = "honos_workingage_subscale_10_adl"
1036 HONOSWA_SUBSCALE_11_LIVINGCONDITIONS = (
1037 "honos_workingage_subscale_11_livingconditions"
1038 )
1039 HONOSWA_SUBSCALE_12_OCCUPATION = "honos_workingage_subscale_12_occupation"
1040 HONOSWA_SCORE = "honos_workingage_observable_score"
1041 HONOSWA_1_OVERACTIVE_SCORE = (
1042 "honos_workingage_observable_1_overactive_score"
1043 )
1044 HONOSWA_2_SELFINJURY_SCORE = (
1045 "honos_workingage_observable_2_selfinjury_score"
1046 )
1047 HONOSWA_3_SUBSTANCE_SCORE = "honos_workingage_observable_3_substance_score"
1048 HONOSWA_4_COGNITIVE_SCORE = "honos_workingage_observable_4_cognitive_score"
1049 HONOSWA_5_PHYSICAL_SCORE = "honos_workingage_observable_5_physical_score"
1050 HONOSWA_6_PSYCHOSIS_SCORE = "honos_workingage_observable_6_psychosis_score"
1051 HONOSWA_7_DEPRESSION_SCORE = (
1052 "honos_workingage_observable_7_depression_score"
1053 )
1054 HONOSWA_8_OTHERMENTAL_SCORE = (
1055 "honos_workingage_observable_8_othermental_score"
1056 )
1057 HONOSWA_9_RELATIONSHIPS_SCORE = (
1058 "honos_workingage_observable_9_relationships_score"
1059 )
1060 HONOSWA_10_ADL_SCORE = "honos_workingage_observable_10_adl_score"
1061 HONOSWA_11_LIVINGCONDITIONS_SCORE = (
1062 "honos_workingage_observable_11_livingconditions_score"
1063 )
1064 HONOSWA_12_OCCUPATION_SCORE = (
1065 "honos_workingage_observable_12_occupation_score"
1066 )
1067 HONOSWA_PROCEDURE_ASSESSMENT = "honos_workingage_procedure_assessment"
1069 # ICD-9-CM: see below; separate file
1071 # ICD-10: see below; separate file
1073 # IDED3D: none
1075 # IES-R
1076 IESR_SCALE = "iesr_scale"
1077 IESR_SCORE = "iesr_observable_score"
1078 IESR_PROCEDURE_ASSESSMENT = "iesr_procedure_assessment"
1080 # INECO Frontal Screening: none
1081 # Khandaker G, Insight: none
1083 # MAST, SMAST
1084 MAST_SCALE = "mast_scale"
1085 MAST_SCORE = "mast_observable_score"
1086 MAST_PROCEDURE_ASSESSMENT = "mast_procedure_assessment"
1088 SMAST_SCALE = "smast_scale"
1089 # SMAST: no observable/procedure
1091 # MDS-UPDRS
1092 UPDRS_SCALE = "updrs_scale"
1093 # MDS-UPDRS: no observable/procedure
1095 # MoCA
1096 MOCA_SCALE = "moca_scale"
1097 MOCA_SCORE = "moca_observable_score"
1098 MOCA_PROCEDURE_ASSESSMENT = "moca_procedure_assessment"
1100 # NART
1101 NART_SCALE = "nart_scale"
1102 NART_SCORE = "nart_observable_score"
1103 NART_PROCEDURE_ASSESSMENT = "nart_procedure_assessment"
1105 # NPI-Q: none
1107 # PANSS
1108 PANSS_SCALE = "panss_scale"
1109 # PANSS: no observable/procedure
1111 # PCL and variants: none
1113 # PDSS
1114 PDSS_SCALE = "pdss_scale"
1115 PDSS_SCORE = "pdss_observable_score"
1116 # PDSS: no procedure
1118 # "Perinatal" and "scale": none
1120 # PHQ-9
1121 PHQ9_FINDING_NEGATIVE_SCREENING_FOR_DEPRESSION = (
1122 "phq9_finding_negative_screening_for_depression"
1123 )
1124 PHQ9_FINDING_POSITIVE_SCREENING_FOR_DEPRESSION = (
1125 "phq9_finding_positive_screening_for_depression"
1126 )
1127 PHQ9_SCORE = "phq9_observable_score"
1128 PHQ9_PROCEDURE_DEPRESSION_SCREENING = "phq9_procedure_depression_screening"
1129 PHQ9_SCALE = (
1130 "phq9_scale" # https://snomedbrowser.com/Codes/Details/758711000000105
1131 )
1133 # PHQ-15
1134 PHQ15_SCORE = "phq15_observable_score"
1135 PHQ15_PROCEDURE = "phq15_procedure_assessment"
1136 PHQ15_SCALE = "phq15_scale"
1138 # PIIOS or "parent infant scale": none
1140 # PSWQ
1141 PSWQ_SCALE = "pswq_scale"
1142 PSWQ_SCORE = "pswq_observable_score"
1143 PSWQ_PROCEDURE_ASSESSMENT = "pswq_procedure_assessment"
1145 # QOL-Basic, QOL-SG
1146 # Unsure, but there is this:
1147 QOL_SCALE = "qol_scale"
1148 # ... with no observable/procedure
1150 # RAND-36: none directly
1152 # SLUMS: none
1154 # WEMWBS, SWEMWBS
1155 WEMWBS_SCALE = "wemwbs_scale"
1156 WEMWBS_SCORE = "wemwbs_observable_score"
1157 WEMWBS_PROCEDURE_ASSESSMENT = "wemwbs_procedure_assessment"
1158 #
1159 SWEMWBS_SCALE = "swemwbs_scale"
1160 SWEMWBS_SCORE = "swemwbs_observable_score"
1161 SWEMWBS_PROCEDURE_ASSESSMENT = "swemwbs_procedure_assessment"
1163 # WSAS
1164 WSAS_SCALE = "wsas_scale"
1165 WSAS_SCORE = "wsas_observable_score"
1166 WSAS_WORK_SCORE = "wsas_observable_work_score"
1167 WSAS_RELATIONSHIPS_SCORE = "wsas_observable_relationships_score"
1168 WSAS_HOME_MANAGEMENT_SCORE = "wsas_observable_home_management_score"
1169 WSAS_SOCIAL_LEISURE_SCORE = "wsas_observable_social_leisure_score"
1170 WSAS_PRIVATE_LEISURE_SCORE = "wsas_observable_private_leisure_score"
1171 WSAS_PROCEDURE_ASSESSMENT = "wsas_procedure_assessment"
1173 # Y-BOCS, Y-BOCS-SC: none
1174 # ZBI: none
1177# -----------------------------------------------------------------------------
1178# Perform the lookup
1179# -----------------------------------------------------------------------------
1181VALID_SNOMED_LOOKUPS = set(
1182 [
1183 getattr(SnomedLookup, k)
1184 for k in dir(SnomedLookup)
1185 if not k.startswith("_")
1186 ]
1187)
1190@cache_region_static.cache_on_arguments(function_key_generator=fkg)
1191def get_all_task_snomed_concepts(
1192 xml_filename: str,
1193) -> Dict[str, SnomedConcept]:
1194 """
1195 Reads in all SNOMED-CT codes for CamCOPS tasks, from the custom CamCOPS XML
1196 file for this.
1198 Args:
1199 xml_filename: XML filename to read
1201 Returns:
1202 dict: maps lookup strings to :class:`SnomedConcept` objects
1204 """
1205 xml_concepts = get_snomed_concepts_from_xml(xml_filename)
1206 camcops_concepts = {} # type: Dict[str, SnomedConcept]
1207 identifiers_seen = set() # type: Set[int]
1208 for lookup, concepts in xml_concepts.items():
1209 # Check it
1210 if lookup not in VALID_SNOMED_LOOKUPS:
1211 log.debug("Ignoring unknown SNOMED-CT lookup: {!r}", lookup)
1212 continue
1213 assert (
1214 len(concepts) == 1 # type: ignore[arg-type]
1215 ), f"More than one SNOMED-CT concept for lookup: {lookup!r}"
1216 concept = concepts[0] # type: ignore[index]
1217 assert (
1218 concept.identifier not in identifiers_seen
1219 ), f"Duplicate SNOMED-CT identifier: {concept.identifier!r}"
1220 identifiers_seen.add(concept.identifier)
1221 # Stash it
1222 camcops_concepts[lookup] = concept
1223 # Check if any are missing
1224 missing = sorted(list(VALID_SNOMED_LOOKUPS - set(camcops_concepts.keys())))
1225 if missing:
1226 raise ValueError(
1227 f"The following SNOMED-CT concepts required by CamCOPS are "
1228 f"missing from the XML ({xml_filename}): {missing!r}"
1229 )
1230 # Done
1231 return camcops_concepts
1234# =============================================================================
1235# UMLS ICD-9-CM
1236# =============================================================================
1239class UmlsIcd9SnomedRow(object):
1240 """
1241 Simple information-holding class for a row of the ICD-9-CM TSV file, from
1242 https://www.nlm.nih.gov/research/umls/mapping_projects/icd9cm_to_snomedct.html.
1244 NOT CURRENTLY USED.
1245 """
1247 HEADER = [
1248 "ICD_CODE",
1249 "ICD_NAME",
1250 "IS_CURRENT_ICD",
1251 "IP_USAGE",
1252 "OP_USAGE",
1253 "AVG_USAGE",
1254 "IS_NEC",
1255 "SNOMED_CID",
1256 "SNOMED_FSN",
1257 "IS_1-1MAP",
1258 "CORE_USAGE",
1259 "IN_CORE",
1260 ]
1262 @staticmethod
1263 def to_float(x: str) -> Optional[float]:
1264 return None if x == "NULL" else float(x)
1266 def __init__(
1267 self,
1268 icd_code: str,
1269 icd_name: str,
1270 is_current_icd: str,
1271 ip_usage: str,
1272 op_usage: str,
1273 avg_usage: str,
1274 is_nec: str,
1275 snomed_cid: str,
1276 snomed_fsn: str,
1277 is_one_to_one_map: str,
1278 core_usage: str,
1279 in_core: str,
1280 ) -> None:
1281 """
1282 Argument order is important.
1284 Args:
1285 icd_code: ICD-9-CM code
1286 icd_name: Name of ICD-9-CM entity
1287 is_current_icd: ?
1288 ip_usage: ?
1289 op_usage: ?
1290 avg_usage: ?
1291 is_nec: ?
1292 snomed_cid: SNOMED-CT concept ID
1293 snomed_fsn: SNOMED-CT fully specified name
1294 is_one_to_one_map: ?; possibly always true in this dataset but not
1295 true in a broader dataset including things other than 1:1
1296 mappings?
1297 core_usage: ?
1298 in_core: ?
1299 """
1300 self.icd_code = icd_code
1301 self.icd_name = icd_name
1302 self.is_current_icd = bool(int(is_current_icd))
1303 self.ip_usage = self.to_float(ip_usage)
1304 self.op_usage = self.to_float(op_usage)
1305 self.avg_usage = self.to_float(avg_usage)
1306 self.is_nec = bool(int(is_nec))
1307 self.snomed_cid = int(snomed_cid)
1308 self.snomed_fsn = snomed_fsn
1309 self.is_one_to_one_map = bool(int(is_one_to_one_map))
1310 self.core_usage = self.to_float(core_usage)
1311 self.in_core = bool(int(in_core))
1313 def __repr__(self) -> str:
1314 return simple_repr(
1315 self,
1316 [
1317 "icd_code",
1318 "icd_name",
1319 "is_current_icd",
1320 "ip_usage",
1321 "op_usage",
1322 "avg_usage",
1323 "is_nec",
1324 "snomed_cid",
1325 "snomed_fsn",
1326 "is_one_to_one_map",
1327 "core_usage",
1328 "in_core",
1329 ],
1330 )
1332 def snomed_concept(self) -> SnomedConcept:
1333 """
1334 Returns the associated SNOMED-CT concept.
1335 """
1336 return SnomedConcept(self.snomed_cid, self.snomed_fsn)
1338 def __str__(self) -> str:
1339 return (
1340 f"ICD-9-CM {self.icd_code} ({self.icd_name}) "
1341 f"-> SNOMED-CT {self.snomed_concept()}"
1342 )
1345@cache_region_static.cache_on_arguments(function_key_generator=fkg)
1346def get_all_icd9cm_snomed_concepts_from_umls(
1347 tsv_filename: str,
1348) -> Dict[str, SnomedConcept]:
1349 """
1350 Reads in all ICD-9-CM SNOMED-CT codes that are supported by the client,
1351 from the UMLS data file, from
1352 https://www.nlm.nih.gov/research/umls/mapping_projects/icd9cm_to_snomedct.html.
1354 Args:
1355 tsv_filename: TSV filename to read
1357 Returns:
1358 dict: maps lookup strings to :class:`SnomedConcept` objects
1360 NOT CURRENTLY USED.
1361 """
1362 log.info("Loading SNOMED-CT ICD-9-CM codes from file: {}", tsv_filename)
1363 concepts = {} # type: Dict[str, SnomedConcept]
1364 with open(tsv_filename, "r") as tsvin:
1365 reader = csv.reader(tsvin, delimiter="\t")
1366 header = next(reader, None)
1367 if header != UmlsIcd9SnomedRow.HEADER:
1368 raise ValueError(
1369 f"ICD-9-CM TSV file has unexpected header: {header!r}; "
1370 f"expected {UmlsIcd9SnomedRow.HEADER!r}"
1371 )
1372 for row in reader:
1373 entry = UmlsIcd9SnomedRow(*row)
1374 if entry.icd_code not in CLIENT_ICD9CM_CODES:
1375 continue
1376 if not entry.is_one_to_one_map:
1377 continue
1378 if entry.icd_code in concepts:
1379 log.warning(
1380 "Duplicate ICD-9-CM code found in SNOMED file "
1381 "{!r}: {!r}",
1382 tsv_filename,
1383 entry.icd_code,
1384 )
1385 continue
1386 concept = entry.snomed_concept()
1387 # log.debug("{}", entry)
1388 concepts[entry.icd_code] = concept
1389 missing = CLIENT_ICD9CM_CODES - set(concepts.keys())
1390 if missing:
1391 log.info(
1392 "No SNOMED-CT codes for ICD-9-CM codes: {}",
1393 ", ".join(sorted(missing)),
1394 )
1395 return concepts
1398# =============================================================================
1399# UMLS ICD-10
1400# =============================================================================
1403class UmlsSnomedToIcd10Row(object):
1404 """
1405 Simple information-holding class for a row of the ICD-10-CM TSV file from
1406 https://www.nlm.nih.gov/research/umls/mapping_projects/snomedct_to_icd10cm.html.
1408 However, that is unhelpful (many to one).
1410 NOT CURRENTLY USED.
1411 """
1413 HEADER = [
1414 "id",
1415 "effectiveTime",
1416 "active",
1417 "moduleId",
1418 "refsetId",
1419 "referencedComponentId",
1420 "referencedComponentName",
1421 "mapGroup",
1422 "mapPriority",
1423 "mapRule",
1424 "mapAdvice",
1425 "mapTarget",
1426 "mapTargetName",
1427 "correlationId",
1428 "mapCategoryId",
1429 "mapCategoryName",
1430 ]
1431 MAP_GOOD = "MAP SOURCE CONCEPT IS PROPERLY CLASSIFIED"
1433 def __init__(
1434 self,
1435 row_id: str,
1436 effective_time: str,
1437 active: str,
1438 module_id: str,
1439 refset_id: str,
1440 referenced_component_id: str,
1441 referenced_component_name: str,
1442 map_group: str,
1443 map_priority: str,
1444 map_rule: str,
1445 map_advice: str,
1446 map_target: str,
1447 map_target_name: str,
1448 correlation_id: str,
1449 map_category_id: str,
1450 map_category_name: str,
1451 ) -> None:
1452 """
1453 Argument order is important.
1455 Args:
1456 row_id: UUID format or similar
1457 effective_time: date in YYYYMMDD format
1458 active: ?
1459 module_id: ?
1460 refset_id: ?
1461 referenced_component_id: SNOMED-CT concept ID
1462 referenced_component_name: SNOMED-CT concept name
1463 map_group: ?; e.g. 1
1464 map_priority: ? but e.g. 1, 2; correlates with map_rule
1465 map_rule: ?; e.g. "TRUE"; "OTHERWISE TRUE"
1466 map_advice: ?, but e.g. "ALWAYS F32.2" or "ALWAYS F32.2 |
1467 DESCENDANTS NOT EXHAUSTIVELY MAPPED"
1468 map_target: ICD-10 code
1469 map_target_name: ICD-10 name
1470 correlation_id: a SNOMED-CT concept for the mapping, e.g.
1471 447561005 = "SNOMED CT source code to target map code
1472 correlation not specified (foundation metadata concept)"
1473 map_category_id: a SNOMED-CT concept for the mapping, e.g.
1474 447637006 = "Map source concept is properly classified
1475 (foundation metadata concept)"
1476 map_category_name: SNOMED-CT name corresponding to map_category_id,
1477 e.g. "MAP SOURCE CONCEPT IS PROPERLY CLASSIFIED"
1478 """
1479 self.row_id = row_id
1480 self.effective_time = effective_time
1481 self.active = bool(int(active))
1482 self.module_id = int(module_id)
1483 self.refset_id = int(refset_id)
1484 self.referenced_component_id = int(referenced_component_id)
1485 self.referenced_component_name = referenced_component_name
1486 self.map_group = int(map_group)
1487 self.map_priority = int(map_priority)
1488 self.map_rule = map_rule
1489 self.map_advice = map_advice
1490 self.map_target = map_target
1491 self.map_target_name = map_target_name
1492 self.correlation_id = int(correlation_id)
1493 self.map_category_id = int(map_category_id)
1494 self.map_category_name = map_category_name
1496 def __repr__(self) -> str:
1497 return simple_repr(
1498 self,
1499 [
1500 "row_id",
1501 "effective_time",
1502 "active",
1503 "module_id",
1504 "refset_id",
1505 "referenced_component_id",
1506 "referenced_component_name",
1507 "map_group",
1508 "map_priority",
1509 "map_rule",
1510 "map_advice",
1511 "map_target",
1512 "map_target_name",
1513 "correlation_id",
1514 "map_category_id",
1515 "map_category_name",
1516 ],
1517 )
1519 def snomed_concept(self) -> SnomedConcept:
1520 """
1521 Returns the associated SNOMED-CT concept.
1522 """
1523 return SnomedConcept(
1524 self.referenced_component_id, self.referenced_component_name
1525 )
1527 @property
1528 def icd_code(self) -> str:
1529 return self.map_target
1531 @property
1532 def icd_name(self) -> str:
1533 return self.map_target_name
1535 def __str__(self) -> str:
1536 return (
1537 f"ICD-10 {self.icd_code} ({self.icd_name}) "
1538 f"-> SNOMED-CT {self.snomed_concept()}"
1539 )
1542def get_all_icd10_snomed_concepts_from_umls(
1543 tsv_filename: str,
1544) -> Dict[str, SnomedConcept]:
1545 """
1546 Reads in all ICD-10 SNOMED-CT codes that are supported by the client,
1547 from the UMLS data file, from
1548 https://www.nlm.nih.gov/research/umls/mapping_projects/snomedct_to_icd10cm.html.
1550 Args:
1551 tsv_filename: TSV filename to read
1553 Returns:
1554 dict: maps lookup strings to :class:`SnomedConcept` objects
1556 NOT CURRENTLY USED.
1557 """
1558 log.info("Loading SNOMED-CT ICD-10-CM codes from file: {}", tsv_filename)
1559 concepts = {} # type: Dict[str, SnomedConcept]
1560 with open(tsv_filename, "r") as tsvin:
1561 reader = csv.reader(tsvin, delimiter="\t")
1562 header = next(reader, None)
1563 if header != UmlsSnomedToIcd10Row.HEADER:
1564 raise ValueError(
1565 f"ICD-9-CM TSV file has unexpected header: {header!r}; "
1566 f"expected {UmlsSnomedToIcd10Row.HEADER!r}"
1567 )
1568 for row in reader:
1569 entry = UmlsSnomedToIcd10Row(*row)
1570 if entry.icd_code not in CLIENT_ICD10_CODES:
1571 continue
1572 if entry.icd_code in concepts:
1573 log.warning(
1574 "Duplicate ICD-10-CM code found in SNOMED file "
1575 "{!r}: {!r}",
1576 tsv_filename,
1577 entry.icd_code,
1578 )
1579 continue
1580 concept = entry.snomed_concept()
1581 # log.debug("{}", entry)
1582 concepts[entry.icd_code] = concept
1583 missing = CLIENT_ICD10_CODES - set(concepts.keys())
1584 if missing:
1585 log.info(
1586 "No SNOMED-CT codes for ICD-10 codes: {}",
1587 ", ".join(sorted(missing)),
1588 )
1589 return concepts
1592# =============================================================================
1593# Athena OHDSI mapping
1594# =============================================================================
1596# -----------------------------------------------------------------------------
1597# Fetch ICD-9-CM and ICD-10 codes (shared for fewer passes through the files)
1598# -----------------------------------------------------------------------------
1601def get_icd9cm_icd10_snomed_concepts_from_athena(
1602 athena_concept_tsv_filename: str,
1603 athena_concept_relationship_tsv_filename: str,
1604) -> Tuple[Dict[str, List[SnomedConcept]], Dict[str, List[SnomedConcept]]]:
1605 """
1606 Takes Athena concept and concept-relationship files, and fetches details
1607 of SNOMED-CT code for all ICD-9-CM and ICD-10[-CM] codes used by CamCOPS.
1609 A bit of human review is required; this is probably preferable to using
1610 gensim or some other automatic similarity check.
1612 Args:
1613 athena_concept_tsv_filename:
1614 path to ``CONCEPT.csv`` (a tab-separated value file)
1615 athena_concept_relationship_tsv_filename:
1616 path to ``CONCEPT_RELATIONSHIP.csv`` (a tab-separated value file)
1618 Returns:
1619 tuple: ``icd9cm, icd10``, where each is a dictionary mapping ICD codes
1620 to a list of mapped :class:`SnomedConcept` objects.
1622 """
1623 athena_icd_concepts = get_athena_concepts(
1624 tsv_filename=athena_concept_tsv_filename,
1625 vocabulary_ids={AthenaVocabularyId.ICD9CM, AthenaVocabularyId.ICD10CM},
1626 concept_codes=CLIENT_ICD9CM_CODES | CLIENT_ICD10_CODES,
1627 )
1628 athena_icd_concepts.sort(key=lambda x: x.concept_code)
1629 relationships = get_athena_concept_relationships(
1630 tsv_filename=athena_concept_relationship_tsv_filename,
1631 concept_id_1_values=set(x.concept_id for x in athena_icd_concepts),
1632 relationship_id_values={AthenaRelationshipId.MAPS_TO},
1633 )
1634 athena_snomed_concepts = get_athena_concepts(
1635 tsv_filename=athena_concept_tsv_filename,
1636 vocabulary_ids={AthenaVocabularyId.SNOMED},
1637 concept_ids=set(x.concept_id_2 for x in relationships),
1638 )
1639 snomed_concepts_icd9 = (
1640 OrderedDict()
1641 ) # type: Dict[str, List[SnomedConcept]]
1642 snomed_concepts_icd10 = (
1643 OrderedDict()
1644 ) # type: Dict[str, List[SnomedConcept]]
1645 for icd in athena_icd_concepts:
1646 target = (
1647 snomed_concepts_icd9
1648 if icd.vocabulary_id == AthenaVocabularyId.ICD9CM
1649 else snomed_concepts_icd10
1650 )
1651 icd_code = icd.concept_code
1652 # log.debug("Processing icd = {}", icd)
1653 possible_snomed = [] # type: List[AthenaConceptRow]
1654 for rel in relationships:
1655 if rel.concept_id_1 != icd.concept_id:
1656 continue
1657 # log.debug("Processing rel = {}", rel)
1658 for snomed in athena_snomed_concepts:
1659 if snomed.concept_id != rel.concept_id_2:
1660 continue
1661 # log.debug("Processing snomed = {}", snomed)
1662 possible_snomed.append(snomed)
1663 if possible_snomed:
1664 sclist = [
1665 SnomedConcept.create(s.snomed_concept())
1666 for s in possible_snomed
1667 ]
1668 sclist.sort(key=lambda sc: sc.identifier)
1669 log.debug("Mapping {} -> {}", icd, sclist)
1670 target[icd_code] = sclist
1671 else:
1672 log.debug("No SNOMED code found for {}", icd)
1673 return snomed_concepts_icd9, snomed_concepts_icd10
1676# -----------------------------------------------------------------------------
1677# Fetch codes from Athena data set and write them to CamCOPS XML
1678# -----------------------------------------------------------------------------
1681def send_athena_icd_snomed_to_xml(
1682 athena_concept_tsv_filename: str,
1683 athena_concept_relationship_tsv_filename: str,
1684 icd9_xml_filename: str,
1685 icd10_xml_filename: str,
1686) -> None:
1687 """
1688 Reads SNOMED-CT codes for ICD-9-CM and ICD10 from Athena OHDSI files, and
1689 writes
1691 Args:
1692 athena_concept_tsv_filename:
1693 path to ``CONCEPT.csv`` (a tab-separated value file)
1694 athena_concept_relationship_tsv_filename:
1695 path to ``CONCEPT_RELATIONSHIP.csv`` (a tab-separated value file)
1696 icd9_xml_filename:
1697 ICD-9 XML filename to write
1698 icd10_xml_filename:
1699 ICD-10 XML filename to write
1700 """
1701 icd9, icd10 = get_icd9cm_icd10_snomed_concepts_from_athena(
1702 athena_concept_tsv_filename=athena_concept_tsv_filename,
1703 athena_concept_relationship_tsv_filename=athena_concept_relationship_tsv_filename, # noqa
1704 )
1705 write_snomed_concepts_to_xml(icd9_xml_filename, icd9)
1706 write_snomed_concepts_to_xml(icd10_xml_filename, icd10)
1709# -----------------------------------------------------------------------------
1710# Fetch data from XML
1711# -----------------------------------------------------------------------------
1714def get_multiple_snomed_concepts_from_xml(
1715 xml_filename: str,
1716 valid_lookups: Set[str] = None,
1717 require_all: bool = False,
1718) -> Dict[str, List[SnomedConcept]]:
1719 """
1720 Reads in all SNOMED-CT codes for ICD-9 or ICD-10, from the custom CamCOPS
1721 XML file for this (made by e.g. :func:`send_athena_icd_snomed_to_xml`).
1723 Args:
1724 xml_filename: XML filename to read
1725 valid_lookups: possible lookup values
1726 require_all: require that ``valid_lookups`` is truthy and that all
1727 values in it are present in the XML
1729 Returns:
1730 dict: maps lookup strings to lists of :class:`SnomedConcept` objects
1732 """
1733 valid_lookups = set(valid_lookups or []) # type: Set[str]
1734 xml_concepts = get_snomed_concepts_from_xml(xml_filename)
1735 camcops_concepts = {} # type: Dict[str, List[SnomedConcept]]
1736 for lookup, concepts in xml_concepts.items():
1737 # Check it
1738 if valid_lookups and lookup not in valid_lookups:
1739 log.debug("Ignoring unknown SNOMED-CT lookup: {!r}", lookup)
1740 continue
1741 # Stash it
1742 camcops_concepts[lookup] = concepts # type: ignore[assignment]
1743 if require_all:
1744 # Check if any are missing
1745 assert valid_lookups, "require_all specified but valid_lookups missing"
1746 if valid_lookups:
1747 missing = sorted(list(valid_lookups - set(camcops_concepts.keys())))
1748 if missing:
1749 msg = (
1750 f'The following {"required " if require_all else ""}'
1751 f"SNOMED-CT concepts are missing from the XML "
1752 f"({xml_filename!r}): {missing!r}"
1753 )
1754 if require_all:
1755 log.critical(msg)
1756 raise ValueError(msg)
1757 else:
1758 log.debug(msg)
1759 # Done
1760 return camcops_concepts
1763@cache_region_static.cache_on_arguments(function_key_generator=fkg)
1764def get_icd9_snomed_concepts_from_xml(
1765 xml_filename: str,
1766) -> Dict[str, List[SnomedConcept]]:
1767 """
1768 Reads in all ICD-9-CM SNOMED-CT codes from a custom CamCOPS XML file.
1770 Args:
1771 xml_filename: filename to read
1773 Returns:
1774 dict: maps ICD-9-CM codes to lists of :class:`SnomedConcept` objects
1775 """
1776 return get_multiple_snomed_concepts_from_xml(
1777 xml_filename, CLIENT_ICD9CM_CODES
1778 )
1781@cache_region_static.cache_on_arguments(function_key_generator=fkg)
1782def get_icd10_snomed_concepts_from_xml(
1783 xml_filename: str,
1784) -> Dict[str, List[SnomedConcept]]:
1785 """
1786 Reads in all ICD-10 SNOMED-CT codes from a custom CamCOPS XML file.
1788 Args:
1789 xml_filename: filename to read
1791 Returns:
1792 dict: maps ICD-10 codes to lists of :class:`SnomedConcept` objects
1793 """
1794 return get_multiple_snomed_concepts_from_xml(
1795 xml_filename, CLIENT_ICD10_CODES
1796 )