As with any project, there are a number of things that could be done to improve it.
Any sort of speed up would be nice. Currently, Pysco will by used if avaliable. Shedskin and PyPy are options for futher improvments.
As well as this, algorithmic speed ups and optimizations would be good.
Chemical Organization Theory prob catalysis RAF sets size of F to size of set overlapping F for sample RA set